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ATG2A

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GENERAL INFORMATION

Gene name

 ATG2A

Gene description

 Autophagy related 2A

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the cytosol. In addition localized to the nucleus & vesicles.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Cytosol (approved)

Additional location

 In addition localized to the Nucleus (approved), Vesicles (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA038715
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the cytosol. In addition localized to the nucleus & vesicles.

Main location

 Cytosol (approved)

Additional location

 Nucleus (approved), Vesicles (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA038715 A-431 Nucleus
Vesicles
Cytosol
HPA038715 U-251 MG Cytosol

GENE INFORMATION

Gene name

 ATG2A (HGNC Symbol)

Synonyms

 KIAA0404

Description

 Autophagy related 2A (HGNC Symbol)

Entrez gene summary

Chromosome

 11

Cytoband

 q13.1

Chromosome location (bp)

 64894546 - 64917248

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000110046 (version 83.38)

Entrez gene

 23130

UniProt

 Q2TAZ0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q2TAZ0

Antibodypedia

 ATG2A antibodies

PROTEIN BROWSER
ATG2A-001
ATG2A-004
ATG2A-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ATG2A-001
ENSP00000366475
ENST00000377264
Q2TAZ0 [Direct mapping]
Autophagy-related protein 2 homolog A
Show all
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000045 [autophagosome assembly]
GO:0000407 [pre-autophagosomal structure]
GO:0000422 [mitophagy]
GO:0005515 [protein binding]
GO:0005811 [lipid particle]
GO:0006995 [cellular response to nitrogen starvation]
GO:0019898 [extrinsic component of membrane]
GO:0034045 [pre-autophagosomal structure membrane]
GO:0044804 [nucleophagy]
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 1938 aa
212.9 kDa 		No 0
ATG2A-004
ENSP00000413716
ENST00000418259
H7C3T2 [Direct mapping]
Autophagy-related protein 2 homolog A
Show all
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000045 [autophagosome assembly]
GO:0000407 [pre-autophagosomal structure]
GO:0000422 [mitophagy]
GO:0006995 [cellular response to nitrogen starvation]
GO:0019898 [extrinsic component of membrane]
GO:0044804 [nucleophagy]
Show all
 1742 aa
190.6 kDa 		No 0
ATG2A-201
ENSP00000410522
ENST00000421419
Q2TAZ0 [Direct mapping]
Autophagy-related protein 2 homolog A
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000045 [autophagosome assembly]
GO:0000407 [pre-autophagosomal structure]
GO:0000422 [mitophagy]
GO:0005515 [protein binding]
GO:0005811 [lipid particle]
GO:0006995 [cellular response to nitrogen starvation]
GO:0019898 [extrinsic component of membrane]
GO:0034045 [pre-autophagosomal structure membrane]
GO:0044804 [nucleophagy]
Show all
 331 aa
35.3 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.