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DCPS

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GENERAL INFORMATION

Gene name

 DCPS

Gene description

 Decapping enzyme, scavenger

Protein class

 Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the nucleoplasm. In addition localized to the cytosol.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoplasm (supported)

Additional location

 In addition localized to the Cytosol (supported)

DATA RELIABILITY

Reliability score

 Supported based on 2 antibodies.
HPA039632 , HPA058597
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

 Nucleoplasm (supported)

Additional location

 Cytosol (supported)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA039632 A-431 Nucleoplasm
HPA039632 U-2 OS Nucleoplasm
Mitochondria
HPA039632 U-251 MG Nucleoplasm
HPA058597 A-431 Nucleoplasm
Cytosol
HPA058597 U-2 OS Nucleoplasm
Cytosol
HPA058597 U-251 MG Nucleoplasm
Cytosol

GENE INFORMATION

Gene name

 DCPS (HGNC Symbol)

Synonyms

 HINT-5, HSL1, HSPC015

Description

 Decapping enzyme, scavenger (HGNC Symbol)

Entrez gene summary

Chromosome

 11

Cytoband

 q24.2

Chromosome location (bp)

 126303752 - 126345749

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000110063 (version 83.38)

Entrez gene

 28960

UniProt

 Q96C86 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96C86

Antibodypedia

 DCPS antibodies

PROTEIN BROWSER
DCPS-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DCPS-001
ENSP00000263579
ENST00000263579
Q96C86 [Direct mapping]
m7GpppX diphosphatase
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Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000290 [deadenylation-dependent decapping of nuclear-transcribed mRNA]
GO:0000340 [RNA 7-methylguanosine cap binding]
GO:0003824 [catalytic activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0010467 [gene expression]
GO:0016787 [hydrolase activity]
GO:0036245 [cellular response to menadione]
GO:0043069 [negative regulation of programmed cell death]
GO:0043928 [exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay]
GO:0045292 [mRNA cis splicing, via spliceosome]
GO:0050072 [m7G(5')pppN diphosphatase activity]
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 337 aa
38.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.