Expression of CD5 in cancer - Summary - The Human Protein Atlas

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CD5

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TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

CD5 molecule

Protein class

CD markers, Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA043416	HPA060839	CAB015392	CAB020308

GENE INFORMATION
Gene name	CD5 (HGNC Symbol)
Synonyms	LEU1, T1
Description	CD5 molecule (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q12.2
Chromosome location (bp)	61102395 - 61127852
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000110448 (version 83.38)
Entrez gene	921
UniProt	P06127 (UniProt - Evidence at protein level)
neXtProt	NX_P06127
Antibodypedia	CD5 antibodies

PROTEIN BROWSER

CD5-001	CD5-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD5-001 ENSP00000342681 ENST00000347785	P06127 [Direct mapping] T-cell surface glycoprotein CD5 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0004888 [transmembrane signaling receptor activity] GO:0005044 [scavenger receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006898 [receptor-mediated endocytosis] GO:0008037 [cell recognition] GO:0008283 [cell proliferation] GO:0009897 [external side of plasma membrane] GO:0016020 [membrane] GO:0031295 [T cell costimulation] GO:0097190 [apoptotic signaling pathway] Show all	495 aa 54.6 kDa	Yes	1
CD5-002 ENSP00000440899 ENST00000544014	F5GYK3 [Direct mapping] T-cell surface glycoprotein CD5 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005044 [scavenger receptor activity] GO:0006898 [receptor-mediated endocytosis] GO:0016020 [membrane] Show all	165 aa 18.4 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.