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PITPNM1

GENERAL INFORMATION

Gene name

 PITPNM1

Gene description

 Phosphatidylinositol transfer protein, membrane-associated 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues, most abundant in a subset of cells in fallopian tube.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA060227
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 PITPNM1 (HGNC Symbol)

Synonyms

 DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1

Description

 Phosphatidylinositol transfer protein, membrane-associated 1 (HGNC Symbol)

Entrez gene summary

 PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 [PubMed 15627748]).[supplied by OMIM, Mar 2008]

Chromosome

 11

Cytoband

 q13.2

Chromosome location (bp)

 67491768 - 67506263

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000110697 (version 83.38)

Entrez gene

 9600

UniProt

 O00562 (UniProt - Evidence at protein level)

neXtProt

 NX_O00562

Antibodypedia

 PITPNM1 antibodies

PROTEIN BROWSER
PITPNM1-001
PITPNM1-002
PITPNM1-004
PITPNM1-006
PITPNM1-007
PITPNM1-008
PITPNM1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PITPNM1-001
ENSP00000398787
ENST00000436757
O00562 [Direct mapping]
Membrane-associated phosphatidylinositol transfer protein 1
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005811 [lipid particle]
GO:0006629 [lipid metabolic process]
GO:0006810 [transport]
GO:0007420 [brain development]
GO:0007602 [phototransduction]
GO:0008526 [phosphatidylinositol transporter activity]
GO:0015031 [protein transport]
GO:0015914 [phospholipid transport]
GO:0016020 [membrane]
GO:0030496 [midbody]
GO:0032154 [cleavage furrow]
GO:0032580 [Golgi cisterna membrane]
GO:0046872 [metal ion binding]
Show all
 1243 aa
134.8 kDa 		No 0
PITPNM1-002
ENSP00000437286
ENST00000534749
O00562 [Direct mapping]
Membrane-associated phosphatidylinositol transfer protein 1
A0A024R5I7 [Target identity:100%; Query identity:100%]
Phosphatidylinositol transfer protein, membrane-associated 1, isoform CRA_a
Show all
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005811 [lipid particle]
GO:0006629 [lipid metabolic process]
GO:0006810 [transport]
GO:0007420 [brain development]
GO:0007602 [phototransduction]
GO:0008526 [phosphatidylinositol transporter activity]
GO:0015031 [protein transport]
GO:0015914 [phospholipid transport]
GO:0016020 [membrane]
GO:0030496 [midbody]
GO:0032154 [cleavage furrow]
GO:0032580 [Golgi cisterna membrane]
GO:0046872 [metal ion binding]
Show all
 1244 aa
134.8 kDa 		No 0
PITPNM1-004
ENSP00000434904
ENST00000528559
E9PMZ6 [Direct mapping]
Membrane-associated phosphatidylinositol transfer protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005622 [intracellular]
GO:0006810 [transport]
Show all
 151 aa
17.2 kDa 		No 0
PITPNM1-006
ENSP00000432746
ENST00000524901
E9PNU6 [Direct mapping]
Membrane-associated phosphatidylinositol transfer protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005622 [intracellular]
GO:0006810 [transport]
Show all
 88 aa
9.9 kDa 		No 0
PITPNM1-007
ENSP00000432977
ENST00000532703
E9PMS0 [Direct mapping]
Membrane-associated phosphatidylinositol transfer protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005622 [intracellular]
GO:0006810 [transport]
Show all
 154 aa
17.6 kDa 		No 0
PITPNM1-008
ENSP00000434046
ENST00000533391
E9PSD1 [Direct mapping]
Membrane-associated phosphatidylinositol transfer protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005622 [intracellular]
GO:0006810 [transport]
Show all
 163 aa
18.7 kDa 		No 0
PITPNM1-201
ENSP00000348772
ENST00000356404
O00562 [Direct mapping]
Membrane-associated phosphatidylinositol transfer protein 1
A0A024R5I7 [Target identity:100%; Query identity:100%]
Phosphatidylinositol transfer protein, membrane-associated 1, isoform CRA_a
Show all
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005811 [lipid particle]
GO:0006629 [lipid metabolic process]
GO:0006810 [transport]
GO:0007420 [brain development]
GO:0007602 [phototransduction]
GO:0008526 [phosphatidylinositol transporter activity]
GO:0015031 [protein transport]
GO:0015914 [phospholipid transport]
GO:0016020 [membrane]
GO:0030496 [midbody]
GO:0032154 [cleavage furrow]
GO:0032580 [Golgi cisterna membrane]
GO:0046872 [metal ion binding]
Show all
 1244 aa
134.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.