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POU2AF1

GENERAL INFORMATION

Gene name

 POU2AF1

Gene description

 POU class 2 associating factor 1

Protein class

 Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (lymph node, tonsil)
GTEx:Tissue enhanced (spleen, small intestine)
FANTOM5:Group enriched (tonsil, appendix, spleen, lymph node)

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear and cytoplasmic expression in subsets of lymphoid cells in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded. Antibody staining in cells/structures not annotated, view images.

Reliability score

 Approved based on 1 antibody.
CAB011193
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Tonsil

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (lymph node, tonsil)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (spleen, small intestine)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (tonsil, appendix, spleen, lymph node)

GENE INFORMATION

Gene name

 POU2AF1 (HGNC Symbol)

Synonyms

 OBF1

Description

 POU class 2 associating factor 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 11

Cytoband

 q23.1

Chromosome location (bp)

 111352252 - 111455630

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000110777 (version 83.38)

Entrez gene

 5450

UniProt

 Q16633 (UniProt - Evidence at protein level)

neXtProt

 NX_Q16633

Antibodypedia

 POU2AF1 antibodies

PROTEIN BROWSER
POU2AF1-001
POU2AF1-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
POU2AF1-001
ENSP00000376786
ENST00000393067
Q16633 [Direct mapping]
POU domain class 2-associating factor 1
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Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Mutated cancer genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Disease related genes
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GO:0003677 [DNA binding]
GO:0003712 [transcription cofactor activity]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006959 [humoral immune response]
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 256 aa
27.4 kDa 		No 0
POU2AF1-007
ENSP00000433527
ENST00000531398
E9PKH4 [Direct mapping]
POU domain class 2-associating factor 1
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Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Show all
 127 aa
13.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.