Expression of CD69 in cancer - Summary - The Human Protein Atlas

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CD69

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TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

CD69 molecule

Protein class

CD markers, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Lymphoma

STAINING SUMMARY

HPA050525	CAB002503

GENE INFORMATION
Gene name	CD69 (HGNC Symbol)
Synonyms	CLEC2C
Description	CD69 molecule (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011]
Chromosome	12
Cytoband	p13.31
Chromosome location (bp)	9752486 - 9760901
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000110848 (version 83.38)
Entrez gene	969
UniProt	Q07108 (UniProt - Evidence at protein level)
neXtProt	NX_Q07108
Antibodypedia	CD69 antibodies

PROTEIN BROWSER

CD69-001	CD69-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD69-001 ENSP00000228434 ENST00000228434	Q07108 [Direct mapping] Early activation antigen CD69 Q53ZX0 [Target identity:100%; Query identity:100%] CD69 antigen; CD69 antigen (P60, early T-cell activation antigen), isoform CRA_a; cDNA FLJ75888, highly similar to Homo sapiens CD69 antigen (p60, early T-cell activation antigen) (CD69), mRNA Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004888 [transmembrane signaling receptor activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0007165 [signal transduction] GO:0009897 [external side of plasma membrane] GO:0030246 [carbohydrate binding] GO:0035690 [cellular response to drug] Show all	199 aa 22.6 kDa	No	1
CD69-003 ENSP00000442597 ENST00000536709	B4E009 [Direct mapping] Early activation antigen CD69; cDNA FLJ55409, highly similar to Early activation antigen CD69 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	164 aa 18.5 kDa	No	1

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.