Expression of CLEC2B in cancer - Summary

CANCER ATLAS

Gene description

C-type lectin domain family 2, member B

Protein class

Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA008194

GENE INFORMATION
Gene name	CLEC2B (HGNC Symbol)
Synonyms	AICL, CLECSF2, HP10085
Description	C-type lectin domain family 2, member B (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	p13.31
Chromosome location (bp)	9852984 - 9870136
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000110852 (version 83.38)
Entrez gene	9976
UniProt	Q92478 (UniProt - Evidence at protein level)
neXtProt	NX_Q92478
Antibodypedia	CLEC2B antibodies

PROTEIN BROWSER

CLEC2B-001	CLEC2B-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CLEC2B-001 ENSP00000228438 ENST00000228438	Q92478 [Direct mapping] C-type lectin domain family 2 member B Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0030246 [carbohydrate binding] GO:0050776 [regulation of immune response] Show all	149 aa 17.3 kDa	Yes	0
CLEC2B-004 ENSP00000437946 ENST00000538152	F5H631 [Direct mapping] C-type lectin domain family 2 member B Show all	Predicted intracellular proteins Show all		80 aa 9.2 kDa	No	0