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CAPRIN2

GENERAL INFORMATION

Gene name

 CAPRIN2

Gene description

 Caprin family member 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 10
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in neuronal cells in CNS and basal cells of testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Supported based on 1 antibody.
HPA039746
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CAPRIN2 (HGNC Symbol)

Synonyms

 C1QDC1, caprin-2, EEG1, FLJ11391, FLJ22569, RNG140

Description

 Caprin family member 2 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene may be involved in the transitioning of erythroblasts from a highly proliferative state to a terminal phase of differentiation. High level expression of the encoded protein can lead to apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Chromosome

 12

Cytoband

 p11.21

Chromosome location (bp)

 30709552 - 30754951

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000110888 (version 83.38)

Entrez gene

 65981

UniProt

 Q6IMN6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6IMN6

Antibodypedia

 CAPRIN2 antibodies

PROTEIN BROWSER
CAPRIN2-001
CAPRIN2-002
CAPRIN2-004
CAPRIN2-005
CAPRIN2-007
CAPRIN2-008
CAPRIN2-009
CAPRIN2-010
CAPRIN2-013
CAPRIN2-015

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CAPRIN2-001
ENSP00000298892
ENST00000298892
Q6IMN6 [Direct mapping]
Caprin-2
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005102 [receptor binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005813 [centrosome]
GO:0017148 [negative regulation of translation]
GO:0030308 [negative regulation of cell growth]
GO:0032092 [positive regulation of protein binding]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0043235 [receptor complex]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0050775 [positive regulation of dendrite morphogenesis]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
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 1077 aa
121 kDa 		No 0
CAPRIN2-002
ENSP00000438010
ENST00000537108
F5H142 [Direct mapping]
Caprin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
Show all
 702 aa
79.2 kDa 		No 0
CAPRIN2-004
ENSP00000379150
ENST00000395805
Q6IMN6 [Direct mapping]
Caprin-2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005102 [receptor binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005813 [centrosome]
GO:0017148 [negative regulation of translation]
GO:0030308 [negative regulation of cell growth]
GO:0032092 [positive regulation of protein binding]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0043235 [receptor complex]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0050775 [positive regulation of dendrite morphogenesis]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
Show all
 905 aa
101.9 kDa 		No 0
CAPRIN2-005
ENSP00000391479
ENST00000417045
Q6IMN6 [Direct mapping]
Caprin-2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005102 [receptor binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005813 [centrosome]
GO:0017148 [negative regulation of translation]
GO:0030308 [negative regulation of cell growth]
GO:0032092 [positive regulation of protein binding]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0043235 [receptor complex]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0050775 [positive regulation of dendrite morphogenesis]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
Show all
 960 aa
107.6 kDa 		No 0
CAPRIN2-007
ENSP00000444137
ENST00000541765
F5GZX3 [Direct mapping]
Caprin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 84 aa
9.9 kDa 		No 0
CAPRIN2-008
ENSP00000442295
ENST00000540436
F5H7T6 [Direct mapping]
Caprin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 126 aa
14.5 kDa 		No 0
CAPRIN2-009
ENSP00000441005
ENST00000540584
F5GXI7 [Direct mapping]
Caprin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 119 aa
13.6 kDa 		No 0
CAPRIN2-010
ENSP00000443353
ENST00000542550
F5H5J8 [Direct mapping]
Caprin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 186 aa
21.5 kDa 		No 0
CAPRIN2-013
ENSP00000440785
ENST00000543380
F5GYA1 [Direct mapping]
Caprin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 68 aa
7.9 kDa 		No 0
CAPRIN2-015
ENSP00000415407
ENST00000433722
H3BM22 [Direct mapping]
Caprin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
Show all
 706 aa
78.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.