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NUP107

CANCER ATLAS

Gene description

 Nucleoporin 107kDa

Protein class

 Predicted intracellular proteins, Predicted membrane proteins, Transporters

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA024141

GENE INFORMATION

Gene name

 NUP107 (HGNC Symbol)

Synonyms

 NUP84

Description

 Nucleoporin 107kDa (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Chromosome

 12

Cytoband

 q15

Chromosome location (bp)

 68686734 - 68745809

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000111581 (version 83.38)

Entrez gene

 57122

UniProt

 P57740 (UniProt - Evidence at protein level)

neXtProt

 NX_P57740

Antibodypedia

 NUP107 antibodies

PROTEIN BROWSER
NUP107-001
NUP107-003
NUP107-005
NUP107-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NUP107-001
ENSP00000229179
ENST00000229179
P57740 [Direct mapping]
Nuclear pore complex protein Nup107
Show all
Transporters
   Transporter channels and pores
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0000777 [condensed chromosome kinetochore]
GO:0005487 [nucleocytoplasmic transporter activity]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006406 [mRNA export from nucleus]
GO:0006810 [transport]
GO:0007077 [mitotic nuclear envelope disassembly]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008033 [tRNA processing]
GO:0008645 [hexose transport]
GO:0010467 [gene expression]
GO:0010827 [regulation of glucose transport]
GO:0015031 [protein transport]
GO:0015758 [glucose transport]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016925 [protein sumoylation]
GO:0017056 [structural constituent of nuclear pore]
GO:0019048 [modulation by virus of host morphology or physiology]
GO:0019054 [modulation by virus of host process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0031047 [gene silencing by RNA]
GO:0031080 [nuclear pore outer ring]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
GO:0034605 [cellular response to heat]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0051292 [nuclear pore complex assembly]
GO:0055085 [transmembrane transport]
GO:1900034 [regulation of cellular response to heat]
Show all
 925 aa
106.4 kDa 		No 0
NUP107-003
ENSP00000441448
ENST00000539906
P57740 [Direct mapping]
Nuclear pore complex protein Nup107
Show all
Transporters
   Transporter channels and pores
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0000777 [condensed chromosome kinetochore]
GO:0005487 [nucleocytoplasmic transporter activity]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006406 [mRNA export from nucleus]
GO:0006810 [transport]
GO:0007077 [mitotic nuclear envelope disassembly]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008033 [tRNA processing]
GO:0008645 [hexose transport]
GO:0010467 [gene expression]
GO:0010827 [regulation of glucose transport]
GO:0015031 [protein transport]
GO:0015758 [glucose transport]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016925 [protein sumoylation]
GO:0017056 [structural constituent of nuclear pore]
GO:0019048 [modulation by virus of host morphology or physiology]
GO:0019054 [modulation by virus of host process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0031047 [gene silencing by RNA]
GO:0031080 [nuclear pore outer ring]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
GO:0034605 [cellular response to heat]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0051292 [nuclear pore complex assembly]
GO:0055085 [transmembrane transport]
GO:1900034 [regulation of cellular response to heat]
Show all
 896 aa
103.2 kDa 		No 0
NUP107-005
ENSP00000440116
ENST00000538549
F5GY77 [Direct mapping]
Nuclear pore complex protein Nup107
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005643 [nuclear pore]
GO:0006810 [transport]
Show all
 85 aa
9.4 kDa 		No 0
NUP107-201
ENSP00000368185
ENST00000378905
P57740 [Direct mapping]
Nuclear pore complex protein Nup107
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0000777 [condensed chromosome kinetochore]
GO:0005487 [nucleocytoplasmic transporter activity]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006406 [mRNA export from nucleus]
GO:0006810 [transport]
GO:0007077 [mitotic nuclear envelope disassembly]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008033 [tRNA processing]
GO:0008645 [hexose transport]
GO:0010467 [gene expression]
GO:0010827 [regulation of glucose transport]
GO:0015031 [protein transport]
GO:0015758 [glucose transport]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016925 [protein sumoylation]
GO:0017056 [structural constituent of nuclear pore]
GO:0019048 [modulation by virus of host morphology or physiology]
GO:0019054 [modulation by virus of host process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0031047 [gene silencing by RNA]
GO:0031080 [nuclear pore outer ring]
GO:0031965 [nuclear membrane]
GO:0034399 [nuclear periphery]
GO:0034605 [cellular response to heat]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0051292 [nuclear pore complex assembly]
GO:0055085 [transmembrane transport]
GO:1900034 [regulation of cellular response to heat]
Show all
 686 aa
80 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.