Tissue expression of C2CD5 - Summary - The Human Protein Atlas

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C2CD5

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	C2CD5
Gene description	C2 calcium-dependent domain containing 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA046194
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	C2CD5 (HGNC Symbol)
Synonyms	CDP138, KIAA0528
Description	C2 calcium-dependent domain containing 5 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	p12.1
Chromosome location (bp)	22448583 - 22544546
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000111731 (version 83.38)
Entrez gene	9847
UniProt	Q86YS7 (UniProt - Evidence at protein level)
neXtProt	NX_Q86YS7
Antibodypedia	C2CD5 antibodies

PROTEIN BROWSER

C2CD5-001	C2CD5-002	C2CD5-003	C2CD5-005	C2CD5-006	C2CD5-007	C2CD5-010	C2CD5-016

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C2CD5-001 ENSP00000334229 ENST00000333957	Q86YS7 [Direct mapping] C2 domain-containing protein 5 Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005886 [plasma membrane] GO:0005938 [cell cortex] GO:0010828 [positive regulation of glucose transport] GO:0030659 [cytoplasmic vesicle membrane] GO:0031340 [positive regulation of vesicle fusion] GO:0032587 [ruffle membrane] GO:0032869 [cellular response to insulin stimulus] GO:0038028 [insulin receptor signaling pathway via phosphatidylinositol 3-kinase] GO:0061024 [membrane organization] GO:0065002 [intracellular protein transmembrane transport] GO:0090314 [positive regulation of protein targeting to membrane] Show all	1000 aa 110.4 kDa	No	0
C2CD5-002 ENSP00000441951 ENST00000542676	Q86YS7 [Direct mapping] C2 domain-containing protein 5 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005886 [plasma membrane] GO:0005938 [cell cortex] GO:0010828 [positive regulation of glucose transport] GO:0030659 [cytoplasmic vesicle membrane] GO:0031340 [positive regulation of vesicle fusion] GO:0032587 [ruffle membrane] GO:0032869 [cellular response to insulin stimulus] GO:0038028 [insulin receptor signaling pathway via phosphatidylinositol 3-kinase] GO:0061024 [membrane organization] GO:0065002 [intracellular protein transmembrane transport] GO:0090314 [positive regulation of protein targeting to membrane] Show all	1051 aa 116 kDa	No	0
C2CD5-003 ENSP00000388756 ENST00000446597	Q86YS7 [Direct mapping] C2 domain-containing protein 5 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005886 [plasma membrane] GO:0005938 [cell cortex] GO:0010828 [positive regulation of glucose transport] GO:0030659 [cytoplasmic vesicle membrane] GO:0031340 [positive regulation of vesicle fusion] GO:0032587 [ruffle membrane] GO:0032869 [cellular response to insulin stimulus] GO:0038028 [insulin receptor signaling pathway via phosphatidylinositol 3-kinase] GO:0061024 [membrane organization] GO:0065002 [intracellular protein transmembrane transport] GO:0090314 [positive regulation of protein targeting to membrane] Show all	1051 aa 116 kDa	No	0
C2CD5-005 ENSP00000439392 ENST00000536386	Q86YS7 [Direct mapping] C2 domain-containing protein 5 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005886 [plasma membrane] GO:0005938 [cell cortex] GO:0010828 [positive regulation of glucose transport] GO:0030659 [cytoplasmic vesicle membrane] GO:0031340 [positive regulation of vesicle fusion] GO:0032587 [ruffle membrane] GO:0032869 [cellular response to insulin stimulus] GO:0038028 [insulin receptor signaling pathway via phosphatidylinositol 3-kinase] GO:0061024 [membrane organization] GO:0065002 [intracellular protein transmembrane transport] GO:0090314 [positive regulation of protein targeting to membrane] Show all	1053 aa 116.3 kDa	No	0
C2CD5-006 ENSP00000379345 ENST00000396028	Q86YS7 [Direct mapping] C2 domain-containing protein 5 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005886 [plasma membrane] GO:0005938 [cell cortex] GO:0010828 [positive regulation of glucose transport] GO:0030659 [cytoplasmic vesicle membrane] GO:0031340 [positive regulation of vesicle fusion] GO:0032587 [ruffle membrane] GO:0032869 [cellular response to insulin stimulus] GO:0038028 [insulin receptor signaling pathway via phosphatidylinositol 3-kinase] GO:0061024 [membrane organization] GO:0065002 [intracellular protein transmembrane transport] GO:0090314 [positive regulation of protein targeting to membrane] Show all	1042 aa 115 kDa	No	0
C2CD5-007 ENSP00000443204 ENST00000545552	Q86YS7 [Direct mapping] C2 domain-containing protein 5 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005886 [plasma membrane] GO:0005938 [cell cortex] GO:0010828 [positive regulation of glucose transport] GO:0030659 [cytoplasmic vesicle membrane] GO:0031340 [positive regulation of vesicle fusion] GO:0032587 [ruffle membrane] GO:0032869 [cellular response to insulin stimulus] GO:0038028 [insulin receptor signaling pathway via phosphatidylinositol 3-kinase] GO:0061024 [membrane organization] GO:0065002 [intracellular protein transmembrane transport] GO:0090314 [positive regulation of protein targeting to membrane] Show all	1054 aa 116.5 kDa	No	0
C2CD5-010 ENSP00000444857 ENST00000535555	H0YGU7 [Direct mapping] C2 domain-containing protein 5 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		182 aa 20.4 kDa	No	0
C2CD5-016 ENSP00000437935 ENST00000539615	H0YFC4 [Direct mapping] C2 domain-containing protein 5 Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		283 aa 30.9 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.