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A majority of cancer tissues displayed moderate immunoreactivity. Most non-Hodgkins lymphomas as well as a few cases of colorectal and urothelial cancers were strongly stained. A majority of squamous cell carcinomas, endometrial cancers, renal cancers, gliomas and melanomas were weakly stained or negative.
Several hepatocellular carcinomas as well as rare cases of colorectal cancers and melanomas were moderate to strongly stained. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
CEP85L (HGNC Symbol)
Synonyms
bA57K17.2, C6orf204, NY-BR-15
Description
Centrosomal protein 85kDa-like (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene was identified as a breast cancer antigen. Nothing more is known of its function at this time. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]