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SLC26A8

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GENERAL INFORMATION

Gene name

 SLC26A8

Gene description

 Solute carrier family 26 (anion exchanger), member 8

Protein class

 Disease related genes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

 Intracellular,Membrane

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Not detected

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 SLC26A8

Synonyms

Description

 Solute carrier family 26 (anion exchanger), member 8 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010]

Chromosome

 6

Cytoband

 p21.31

Chromosome location (bp)

 35943514 - 36024868

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000112053 (version 83.38)

Entrez gene

 116369

UniProt

 Q96RN1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96RN1

Antibodypedia

 SLC26A8 antibodies

PROTEIN BROWSER
SLC26A8-001
SLC26A8-005
SLC26A8-006
SLC26A8-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC26A8-001
ENSP00000417638
ENST00000490799
Q96RN1 [Direct mapping]
Testis anion transporter 1
A0A024RCV0 [Target identity:100%; Query identity:100%]
Testis anion transporter 1
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Show all
GO:0005254 [chloride channel activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0007275 [multicellular organismal development]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016021 [integral component of membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0030317 [sperm motility]
GO:0042391 [regulation of membrane potential]
GO:0048240 [sperm capacitation]
GO:0051321 [meiotic cell cycle]
GO:0051453 [regulation of intracellular pH]
GO:0098656 [anion transmembrane transport]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 970 aa
109 kDa 		No >9
SLC26A8-005
ENSP00000347778
ENST00000355574
Q96RN1 [Direct mapping]
Testis anion transporter 1
A0A024RCV0 [Target identity:100%; Query identity:100%]
Testis anion transporter 1
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Show all
GO:0005254 [chloride channel activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0007275 [multicellular organismal development]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016021 [integral component of membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0030317 [sperm motility]
GO:0042391 [regulation of membrane potential]
GO:0048240 [sperm capacitation]
GO:0051321 [meiotic cell cycle]
GO:0051453 [regulation of intracellular pH]
GO:0098656 [anion transmembrane transport]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 970 aa
109 kDa 		No >9
SLC26A8-006
ENSP00000378100
ENST00000394602
Q96RN1 [Direct mapping]
Testis anion transporter 1
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Show all
GO:0005254 [chloride channel activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0007275 [multicellular organismal development]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016021 [integral component of membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0030317 [sperm motility]
GO:0042391 [regulation of membrane potential]
GO:0048240 [sperm capacitation]
GO:0051321 [meiotic cell cycle]
GO:0051453 [regulation of intracellular pH]
GO:0098656 [anion transmembrane transport]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 865 aa
97.4 kDa 		No 8
SLC26A8-007
ENSP00000420488
ENST00000480663
C9JMV8 [Direct mapping]
Testis anion transporter 1
Show all
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0016020 [membrane]
GO:0030317 [sperm motility]
GO:0048240 [sperm capacitation]
GO:1902358 [sulfate transmembrane transport]
Show all
 190 aa
21.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.