Expression of KHDRBS2 in cancer - Summary

CANCER ATLAS

Gene description

KH domain containing, RNA binding, signal transduction associated 2

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA000500	HPA029392

Tissue	Cancer staining	Protein expression of normal tissue
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma

Tissue	Cancer staining	Protein expression of normal tissue
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary	Malignant gliomas and carcinoids as well as cases of malignant melanomas, lung, testis, ovarian, renal, breast and prostate cancers exhibited moderate to strong nuclear staining. Remaining malignancies were generally weakly stained or negative.

GENE INFORMATION
Gene name	KHDRBS2 (HGNC Symbol)
Synonyms	MGC26664, SLM-1, SLM1
Description	KH domain containing, RNA binding, signal transduction associated 2 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q11.1
Chromosome location (bp)	61679960 - 62286227
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112232 (version 83.38)
Entrez gene	202559
UniProt	Q5VWX1 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VWX1
Antibodypedia	KHDRBS2 antibodies

PROTEIN BROWSER

KHDRBS2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KHDRBS2-001 ENSP00000281156 ENST00000281156	Q5VWX1 [Direct mapping] KH domain-containing, RNA-binding, signal transduction-associated protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008143 [poly(A) binding] GO:0008266 [poly(U) RNA binding] GO:0017124 [SH3 domain binding] GO:0042169 [SH2 domain binding] GO:0046982 [protein heterodimerization activity] Show all	349 aa 38.9 kDa	No	0