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BVES

CANCER ATLAS

Gene description

 Blood vessel epicardial substance

Protein class

 Predicted membrane proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA014788
HPA018176

GENE INFORMATION

Gene name

 BVES (HGNC Symbol)

Synonyms

 HBVES, POP1, POPDC1

Description

 Blood vessel epicardial substance (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]

Chromosome

 6

Cytoband

 q21

Chromosome location (bp)

 105096822 - 105137174

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000112276 (version 83.38)

Entrez gene

 11149

UniProt

 Q8NE79 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NE79

Antibodypedia

 BVES antibodies

PROTEIN BROWSER
BVES-001
BVES-002
BVES-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BVES-001
ENSP00000337259
ENST00000336775
Q8NE79 [Direct mapping]
Blood vessel epicardial substance
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001921 [positive regulation of receptor recycling]
GO:0005198 [structural molecule activity]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007517 [muscle organ development]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0016328 [lateral plasma membrane]
GO:0034446 [substrate adhesion-dependent cell spreading]
GO:0040017 [positive regulation of locomotion]
GO:0043087 [regulation of GTPase activity]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 360 aa
41.5 kDa 		No 2
BVES-002
ENSP00000397310
ENST00000446408
Q8NE79 [Direct mapping]
Blood vessel epicardial substance
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001921 [positive regulation of receptor recycling]
GO:0005198 [structural molecule activity]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007517 [muscle organ development]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0016328 [lateral plasma membrane]
GO:0034446 [substrate adhesion-dependent cell spreading]
GO:0040017 [positive regulation of locomotion]
GO:0043087 [regulation of GTPase activity]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 360 aa
41.5 kDa 		No 3
BVES-003
ENSP00000313172
ENST00000314641
Q8NE79 [Direct mapping]
Blood vessel epicardial substance
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001921 [positive regulation of receptor recycling]
GO:0002027 [regulation of heart rate]
GO:0002244 [hematopoietic progenitor cell differentiation]
GO:0005198 [structural molecule activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007517 [muscle organ development]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0016328 [lateral plasma membrane]
GO:0030552 [cAMP binding]
GO:0031253 [cell projection membrane]
GO:0034446 [substrate adhesion-dependent cell spreading]
GO:0040017 [positive regulation of locomotion]
GO:0042391 [regulation of membrane potential]
GO:0043087 [regulation of GTPase activity]
GO:0048278 [vesicle docking]
GO:0060931 [sinoatrial node cell development]
GO:0060973 [cell migration involved in heart development]
GO:0090136 [epithelial cell-cell adhesion]
GO:2001135 [regulation of endocytic recycling]
Show all
 360 aa
41.5 kDa 		No 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.