Fields »
ABOUT
HELP
BLOG
TRIM38

GENERAL INFORMATION

Gene name

 TRIM38

Gene description

 Tripartite motif containing 38

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA031685
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 TRIM38 (HGNC Symbol)

Synonyms

 RNF15, RORET

Description

 Tripartite motif containing 38 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012]

Chromosome

 6

Cytoband

 p22.2

Chromosome location (bp)

 25962802 - 25991226

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000112343 (version 83.38)

Entrez gene

 10475

UniProt

 O00635 (UniProt - Evidence at protein level)

neXtProt

 NX_O00635

Antibodypedia

 TRIM38 antibodies

PROTEIN BROWSER
TRIM38-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRIM38-001
ENSP00000349596
ENST00000357085
O00635 [Direct mapping]
E3 ubiquitin-protein ligase TRIM38
A0A024QZY4 [Target identity:100%; Query identity:100%]
Tripartite motif-containing 38, isoform CRA_a
Show all
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0016874 [ligase activity]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0032648 [regulation of interferon-beta production]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0045070 [positive regulation of viral genome replication]
GO:0046598 [positive regulation of viral entry into host cell]
GO:0050687 [negative regulation of defense response to virus]
GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0070936 [protein K48-linked ubiquitination]
Show all
 465 aa
53.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.