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ARFGEF3

CANCER ATLAS

Gene description

 ARFGEF family member 3

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA036350

GENE INFORMATION

Gene name

 ARFGEF3 (HGNC Symbol)

Synonyms

 BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33

Description

 ARFGEF family member 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 6

Cytoband

Chromosome location (bp)

 138161921 - 138344663

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000112379 (version 83.38)

Entrez gene

 57221

UniProt

 Q5TH69 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5TH69

Antibodypedia

 ARFGEF3 antibodies

PROTEIN BROWSER
ARFGEF3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARFGEF3-001
ENSP00000251691
ENST00000251691
Q5TH69 [Direct mapping]
Brefeldin A-inhibited guanine nucleotide-exchange protein 3
C5NM88 [Target identity:100%; Query identity:100%]
Putative uncharacterized protein A7322
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   Phobius predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005086 [ARF guanyl-nucleotide exchange factor activity]
GO:0005488 [binding]
GO:0005802 [trans-Golgi network]
GO:0010923 [negative regulation of phosphatase activity]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0032012 [regulation of ARF protein signal transduction]
GO:0043547 [positive regulation of GTPase activity]
Show all
 2177 aa
240.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.