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Cancers displayed moderate to strong cytoplasmic positivity. Several lymphomas were negative.
GENE INFORMATION
Gene name
SLC39A7 (HGNC Symbol)
Synonyms
D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7
Description
Solute carrier family 39 (zinc transporter), member 7 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]