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A few cases of thyroid, testis, pancreatic, liver cancer and lymphomas and melanomas showed moderate diffuse cytoplasmic positivity sometimes with small granules. Remaining cancers were weakly stained or negative.
GENE INFORMATION
Gene name
SEMA5A (HGNC Symbol)
Synonyms
SEMAF, semF
Description
Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (HGNC Symbol)
Entrez gene summary
This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene.[provided by RefSeq, Jan 2010]