Expression of PAPD7 in cancer - Summary

CANCER ATLAS

Gene description

PAP associated domain containing 7

Protein class

Enzymes, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA045487	HPA046742

GENE INFORMATION
Gene name	PAPD7 (HGNC Symbol)
Synonyms	LAK-1, POLK, POLS, TRF4, TRF4-1
Description	PAP associated domain containing 7 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jan 2010]
Chromosome	5
Cytoband	p15.31
Chromosome location (bp)	6713007 - 6757048
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112941 (version 83.38)
Entrez gene	11044
UniProt	Q5XG87 (UniProt - Evidence at protein level)
neXtProt	NX_Q5XG87
Antibodypedia	PAPD7 antibodies

PROTEIN BROWSER

PAPD7-001	PAPD7-007	PAPD7-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PAPD7-001 ENSP00000230859 ENST00000230859	Q5XG87 [Direct mapping] Non-canonical poly(A) RNA polymerase PAPD7 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003677 [DNA binding] GO:0003887 [DNA-directed DNA polymerase activity] GO:0004652 [polynucleotide adenylyltransferase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006302 [double-strand break repair] GO:0007062 [sister chromatid cohesion] GO:0007076 [mitotic chromosome condensation] GO:0016779 [nucleotidyltransferase activity] GO:0042493 [response to drug] GO:0043221 [SMC family protein binding] GO:0046872 [metal ion binding] GO:0051301 [cell division] GO:0071897 [DNA biosynthetic process] Show all	792 aa 84.6 kDa	No	1
PAPD7-007 ENSP00000427232 ENST00000515721	D6RJD0 [Direct mapping] Non-canonical poly(A) RNA polymerase PAPD7 Show all	Predicted intracellular proteins Show all		27 aa 3.2 kDa	No	0
PAPD7-008 ENSP00000488642 ENST00000631941	Q5XG87 [Direct mapping] Non-canonical poly(A) RNA polymerase PAPD7 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003677 [DNA binding] GO:0003887 [DNA-directed DNA polymerase activity] GO:0004652 [polynucleotide adenylyltransferase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006302 [double-strand break repair] GO:0007062 [sister chromatid cohesion] GO:0007076 [mitotic chromosome condensation] GO:0016779 [nucleotidyltransferase activity] GO:0042493 [response to drug] GO:0043221 [SMC family protein binding] GO:0046872 [metal ion binding] GO:0051301 [cell division] GO:0071897 [DNA biosynthetic process] Show all	542 aa 59.9 kDa	No	1