Expression of CLINT1 in cancer - Summary

CANCER ATLAS

Gene description

Clathrin interactor 1

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA043280	HPA056947

GENE INFORMATION
Gene name	CLINT1 (HGNC Symbol)
Synonyms	CLINT, ENTH, EPNR, KIAA0171
Description	Clathrin interactor 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
Chromosome	5
Cytoband	q33.3
Chromosome location (bp)	157785743 - 157859175
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000113282 (version 83.38)
Entrez gene	9685
UniProt	Q14677 (UniProt - Evidence at protein level)
neXtProt	NX_Q14677
Antibodypedia	CLINT1 antibodies

PROTEIN BROWSER

CLINT1-001	CLINT1-002	CLINT1-003	CLINT1-006	CLINT1-008	CLINT1-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CLINT1-001 ENSP00000388340 ENST00000411809	Q14677 [Direct mapping] Clathrin interactor 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005829 [cytosol] GO:0006892 [post-Golgi vesicle-mediated transport] GO:0006897 [endocytosis] GO:0008289 [lipid binding] GO:0016020 [membrane] GO:0030136 [clathrin-coated vesicle] GO:0030276 [clathrin binding] GO:0043231 [intracellular membrane-bounded organelle] GO:0048471 [perinuclear region of cytoplasm] GO:0061024 [membrane organization] Show all	625 aa 68.3 kDa	No	0
CLINT1-002 ENSP00000429824 ENST00000523908	Q14677 [Direct mapping] Clathrin interactor 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005829 [cytosol] GO:0006892 [post-Golgi vesicle-mediated transport] GO:0006897 [endocytosis] GO:0008289 [lipid binding] GO:0016020 [membrane] GO:0030136 [clathrin-coated vesicle] GO:0030276 [clathrin binding] GO:0043231 [intracellular membrane-bounded organelle] GO:0048471 [perinuclear region of cytoplasm] GO:0061024 [membrane organization] Show all	643 aa 70.3 kDa	No	0
CLINT1-003 ENSP00000429345 ENST00000523094	Q14677 [Direct mapping] Clathrin interactor 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005829 [cytosol] GO:0006892 [post-Golgi vesicle-mediated transport] GO:0006897 [endocytosis] GO:0008289 [lipid binding] GO:0016020 [membrane] GO:0030136 [clathrin-coated vesicle] GO:0030276 [clathrin binding] GO:0043231 [intracellular membrane-bounded organelle] GO:0048471 [perinuclear region of cytoplasm] GO:0061024 [membrane organization] Show all	625 aa 68.2 kDa	No	0
CLINT1-006 ENSP00000433013 ENST00000521615	H0YD52 [Direct mapping] Clathrin interactor 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		133 aa 13.1 kDa	No	0
CLINT1-008 ENSP00000434334 ENST00000522381	H0YDU9 [Direct mapping] Clathrin interactor 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		66 aa 7.3 kDa	No	0
CLINT1-010 ENSP00000433419 ENST00000530742	Q14677 [Direct mapping] Clathrin interactor 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005829 [cytosol] GO:0006892 [post-Golgi vesicle-mediated transport] GO:0006897 [endocytosis] GO:0008289 [lipid binding] GO:0016020 [membrane] GO:0030136 [clathrin-coated vesicle] GO:0030276 [clathrin binding] GO:0043231 [intracellular membrane-bounded organelle] GO:0048471 [perinuclear region of cytoplasm] GO:0061024 [membrane organization] Show all	625 aa 68.2 kDa	No	0