Expression of POLR3G in cancer - Summary

CANCER ATLAS

Gene description

Polymerase (RNA) III (DNA directed) polypeptide G (32kD)

Protein class

Predicted intracellular proteins, RNA polymerase related proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Melanoma

STAINING SUMMARY

CAB010109

GENE INFORMATION
Gene name	POLR3G (HGNC Symbol)
Synonyms	RPC32, RPC7
Description	Polymerase (RNA) III (DNA directed) polypeptide G (32kD) (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q14.3
Chromosome location (bp)	90471748 - 90514553
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000113356 (version 83.38)
Entrez gene	10622
UniProt	O15318 (UniProt - Evidence at protein level)
neXtProt	NX_O15318
Antibodypedia	POLR3G antibodies

PROTEIN BROWSER

POLR3G-001	POLR3G-003	POLR3G-004	POLR3G-005	POLR3G-006	POLR3G-007	POLR3G-201	POLR3G-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
POLR3G-001 ENSP00000421637 ENST00000504930	O15318 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7 A0A024RAM1 [Target identity:100%; Query identity:100%] Polymerase (RNA) III (DNA directed) polypeptide G (32kD), isoform CRA_a Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000790 [nuclear chromatin] GO:0001056 [RNA polymerase III activity] GO:0003899 [DNA-directed RNA polymerase activity] GO:0005654 [nucleoplasm] GO:0005666 [DNA-directed RNA polymerase III complex] GO:0005829 [cytosol] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006383 [transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter] GO:0006385 [transcription elongation from RNA polymerase III promoter] GO:0006386 [termination of RNA polymerase III transcription] GO:0008283 [cell proliferation] GO:0010467 [gene expression] GO:0032481 [positive regulation of type I interferon production] GO:0032728 [positive regulation of interferon-beta production] GO:0045087 [innate immune response] GO:0045089 [positive regulation of innate immune response] GO:0051607 [defense response to virus] Show all	223 aa 25.9 kDa	No	0
POLR3G-003 ENSP00000422164 ENST00000503973	D6R921 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7 Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001056 [RNA polymerase III activity] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter] Show all	127 aa 15 kDa	No	0
POLR3G-004 ENSP00000427412 ENST00000505345	D6RIT0 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7 Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001056 [RNA polymerase III activity] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter] Show all	92 aa 10.7 kDa	No	0
POLR3G-005 ENSP00000422892 ENST00000503373	D6R9U7 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7 Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001056 [RNA polymerase III activity] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter] Show all	221 aa 25.7 kDa	No	0
POLR3G-006 ENSP00000424970 ENST00000512239	D6REQ0 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7 Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001056 [RNA polymerase III activity] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter] Show all	39 aa 4.2 kDa	No	0
POLR3G-007 ENSP00000425617 ENST00000514483	D6RJH6 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7 Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001056 [RNA polymerase III activity] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter] Show all	100 aa 11.4 kDa	No	0
POLR3G-201 ENSP00000382058 ENST00000399107	O15318 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7 A0A024RAM1 [Target identity:100%; Query identity:100%] Polymerase (RNA) III (DNA directed) polypeptide G (32kD), isoform CRA_a Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000790 [nuclear chromatin] GO:0001056 [RNA polymerase III activity] GO:0003899 [DNA-directed RNA polymerase activity] GO:0005654 [nucleoplasm] GO:0005666 [DNA-directed RNA polymerase III complex] GO:0005829 [cytosol] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006383 [transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter] GO:0006385 [transcription elongation from RNA polymerase III promoter] GO:0006386 [termination of RNA polymerase III transcription] GO:0008283 [cell proliferation] GO:0010467 [gene expression] GO:0032481 [positive regulation of type I interferon production] GO:0032728 [positive regulation of interferon-beta production] GO:0045087 [innate immune response] GO:0045089 [positive regulation of innate immune response] GO:0051607 [defense response to virus] Show all	223 aa 25.9 kDa	No	0
POLR3G-202 ENSP00000478166 ENST00000622335	A0A087WTV7 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7 Show all	Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001056 [RNA polymerase III activity] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter] Show all	233 aa 27.3 kDa	No	0