Expression of SUB1 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

SUB1 homolog, transcriptional regulator

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA001311	CAB015351

GENE INFORMATION
Gene name	SUB1 (HGNC Symbol)
Synonyms	p14, p15, PC4
Description	SUB1 homolog, transcriptional regulator (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	p13.3
Chromosome location (bp)	32531633 - 32604079
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000113387 (version 83.38)
Entrez gene	10923
UniProt	P53999 (UniProt - Evidence at protein level)
neXtProt	NX_P53999
Antibodypedia	SUB1 antibodies

PROTEIN BROWSER

SUB1-001	SUB1-006	SUB1-007	SUB1-009	SUB1-011	SUB1-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SUB1-001 ENSP00000265073 ENST00000265073	P53999 [Direct mapping] Activated RNA polymerase II transcriptional coactivator p15 Q6IBA2 [Target identity:100%; Query identity:100%] PC4 protein; SUB1 homolog (S. cerevisiae); SUB1 homolog (S. cerevisiae), isoform CRA_a; cDNA, FLJ92014, highly similar to Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), mRNA Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001205 [transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding] GO:0003677 [DNA binding] GO:0003697 [single-stranded DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005730 [nucleolus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0044822 [poly(A) RNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0060395 [SMAD protein signal transduction] GO:0070062 [extracellular exosome] Show all	127 aa 14.4 kDa	No	0
SUB1-006 ENSP00000426850 ENST00000515355	P53999 [Direct mapping] Activated RNA polymerase II transcriptional coactivator p15 Q6IBA2 [Target identity:100%; Query identity:100%] PC4 protein; SUB1 homolog (S. cerevisiae); SUB1 homolog (S. cerevisiae), isoform CRA_a; cDNA, FLJ92014, highly similar to Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), mRNA Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0003697 [single-stranded DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005730 [nucleolus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0044822 [poly(A) RNA binding] GO:0070062 [extracellular exosome] Show all	127 aa 14.4 kDa	No	0
SUB1-007 ENSP00000427100 ENST00000502897	P53999 [Direct mapping] Activated RNA polymerase II transcriptional coactivator p15 Q6IBA2 [Target identity:100%; Query identity:100%] PC4 protein; SUB1 homolog (S. cerevisiae); SUB1 homolog (S. cerevisiae), isoform CRA_a; cDNA, FLJ92014, highly similar to Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), mRNA Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0003697 [single-stranded DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005730 [nucleolus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0044822 [poly(A) RNA binding] GO:0070062 [extracellular exosome] Show all	127 aa 14.4 kDa	No	0
SUB1-009 ENSP00000423893 ENST00000510442	D6RC37 [Direct mapping] Activated RNA polymerase II transcriptional coactivator p15 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		66 aa 7.2 kDa	No	0
SUB1-011 ENSP00000422078 ENST00000506237	P53999 [Direct mapping] Activated RNA polymerase II transcriptional coactivator p15 Q6IBA2 [Target identity:100%; Query identity:100%] PC4 protein; SUB1 homolog (S. cerevisiae); SUB1 homolog (S. cerevisiae), isoform CRA_a; cDNA, FLJ92014, highly similar to Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), mRNA Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0003697 [single-stranded DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005730 [nucleolus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0044822 [poly(A) RNA binding] GO:0070062 [extracellular exosome] Show all	127 aa 14.4 kDa	No	0
SUB1-012 ENSP00000422806 ENST00000512913	P53999 [Direct mapping] Activated RNA polymerase II transcriptional coactivator p15 Q6IBA2 [Target identity:100%; Query identity:100%] PC4 protein; SUB1 homolog (S. cerevisiae); SUB1 homolog (S. cerevisiae), isoform CRA_a; cDNA, FLJ92014, highly similar to Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), mRNA Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0003697 [single-stranded DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005730 [nucleolus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0044822 [poly(A) RNA binding] GO:0070062 [extracellular exosome] Show all	127 aa 14.4 kDa	No	0