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CSNK1A1

CANCER ATLAS

Gene description

 Casein kinase 1, alpha 1

Protein class

 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
CAB016680

GENE INFORMATION

Gene name

 CSNK1A1 (HGNC Symbol)

Synonyms

 CK1, CK1a, CK1alpha, CKIa, CKIalpha

Description

 Casein kinase 1, alpha 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 q32

Chromosome location (bp)

 149492197 - 149551552

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000113712 (version 83.38)

Entrez gene

 1452

UniProt

 P48729 (UniProt - Evidence at protein level)

neXtProt

 NX_P48729

Antibodypedia

 CSNK1A1 antibodies

PROTEIN BROWSER
CSNK1A1-001
CSNK1A1-002
CSNK1A1-003
CSNK1A1-004
CSNK1A1-005
CSNK1A1-006
CSNK1A1-008
CSNK1A1-009
CSNK1A1-201
CSNK1A1-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CSNK1A1-001
ENSP00000261798
ENST00000261798
P48729 [Direct mapping]
Casein kinase I isoform alpha
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CK1 Ser/Thr protein kinases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000777 [condensed chromosome kinetochore]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005847 [mRNA cleavage and polyadenylation specificity factor complex]
GO:0006468 [protein phosphorylation]
GO:0006909 [phagocytosis]
GO:0007030 [Golgi organization]
GO:0007067 [mitotic nuclear division]
GO:0007165 [signal transduction]
GO:0007166 [cell surface receptor signaling pathway]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016607 [nuclear speck]
GO:0018105 [peptidyl-serine phosphorylation]
GO:0045095 [keratin filament]
GO:0045104 [intermediate filament cytoskeleton organization]
GO:0051301 [cell division]
GO:0072372 [primary cilium]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:1904424 [regulation of GTP binding]
Show all
 325 aa
37.6 kDa 		No 0
CSNK1A1-002
ENSP00000426747
ENST00000504676
D6REM4 [Direct mapping]
Casein kinase I isoform alpha
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0006909 [phagocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
Show all
 236 aa
27.7 kDa 		No 0
CSNK1A1-003
ENSP00000421689
ENST00000515768
P48729 [Direct mapping]
Casein kinase I isoform alpha
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CK1 Ser/Thr protein kinases
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000777 [condensed chromosome kinetochore]
GO:0000902 [cell morphogenesis]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005847 [mRNA cleavage and polyadenylation specificity factor complex]
GO:0006468 [protein phosphorylation]
GO:0006909 [phagocytosis]
GO:0007030 [Golgi organization]
GO:0007067 [mitotic nuclear division]
GO:0007165 [signal transduction]
GO:0007166 [cell surface receptor signaling pathway]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016607 [nuclear speck]
GO:0018105 [peptidyl-serine phosphorylation]
GO:0030529 [ribonucleoprotein complex]
GO:0045095 [keratin filament]
GO:0045104 [intermediate filament cytoskeleton organization]
GO:0051301 [cell division]
GO:0072372 [primary cilium]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:1904424 [regulation of GTP binding]
Show all
 365 aa
41.9 kDa 		No 0
CSNK1A1-004
ENSP00000427031
ENST00000515435
E7ETM0 [Direct mapping]
Casein kinase I isoform alpha
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0006909 [phagocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
Show all
 264 aa
30.8 kDa 		No 0
CSNK1A1-005
ENSP00000421268
ENST00000515748
D6RGE5 [Direct mapping]
Casein kinase I isoform alpha
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0006909 [phagocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
Show all
 89 aa
9.8 kDa 		No 0
CSNK1A1-006
ENSP00000425366
ENST00000503350
H0Y9X2 [Direct mapping]
Casein kinase I isoform alpha
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0006909 [phagocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
Show all
 167 aa
19.3 kDa 		No 0
CSNK1A1-008
ENSP00000475319
ENST00000606719
U3KPX3 [Direct mapping]
Casein kinase I isoform alpha
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0006909 [phagocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
Show all
 134 aa
15.6 kDa 		No 0
CSNK1A1-009
ENSP00000475633
ENST00000606299
U3KQ83 [Direct mapping]
Casein kinase I isoform alpha
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0006909 [phagocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
Show all
 96 aa
11.1 kDa 		No 0
CSNK1A1-201
ENSP00000367074
ENST00000377843
P48729 [Direct mapping]
Casein kinase I isoform alpha
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CK1 Ser/Thr protein kinases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000777 [condensed chromosome kinetochore]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005847 [mRNA cleavage and polyadenylation specificity factor complex]
GO:0006468 [protein phosphorylation]
GO:0006909 [phagocytosis]
GO:0007030 [Golgi organization]
GO:0007067 [mitotic nuclear division]
GO:0007165 [signal transduction]
GO:0007166 [cell surface receptor signaling pathway]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016607 [nuclear speck]
GO:0018105 [peptidyl-serine phosphorylation]
GO:0045095 [keratin filament]
GO:0045104 [intermediate filament cytoskeleton organization]
GO:0051301 [cell division]
GO:0072372 [primary cilium]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:1904424 [regulation of GTP binding]
Show all
 337 aa
38.9 kDa 		No 0
CSNK1A1-202
ENSP00000479826
ENST00000412431
A0A087WW03 [Direct mapping]
Casein kinase 1, alpha 1, isoform CRA_b; Casein kinase I isoform alpha
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0006909 [phagocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0016301 [kinase activity]
GO:0018105 [peptidyl-serine phosphorylation]
Show all
 166 aa
20 kDa 		No 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.