Expression of ERGIC1 in cancer - Summary

CANCER ATLAS

Gene description

Endoplasmic reticulum-golgi intermediate compartment 1

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA018666	HPA018900

GENE INFORMATION
Gene name	ERGIC1 (HGNC Symbol)
Synonyms	ERGIC-32, ERGIC32, KIAA1181, NET24
Description	Endoplasmic reticulum-golgi intermediate compartment 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a cycling membrane protein which is an endoplasmic reticulum-golgi intermediate compartment (ERGIC) protein which interacts with other members of this protein family to increase their turnover. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	q35.1
Chromosome location (bp)	172834275 - 172952685
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000113719 (version 83.38)
Entrez gene	57222
UniProt	Q969X5 (UniProt - Evidence at protein level)
neXtProt	NX_Q969X5
Antibodypedia	ERGIC1 antibodies

PROTEIN BROWSER

ERGIC1-001	ERGIC1-002	ERGIC1-007	ERGIC1-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ERGIC1-001 ENSP00000325127 ENST00000326654	Q969X5 [Direct mapping] Endoplasmic reticulum-Golgi intermediate compartment protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] Show all	159 aa 17.8 kDa	No	0
ERGIC1-002 ENSP00000377374 ENST00000393784	Q969X5 [Direct mapping] Endoplasmic reticulum-Golgi intermediate compartment protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] Show all	290 aa 32.6 kDa	No	2
ERGIC1-007 ENSP00000429501 ENST00000518247	F2Z3Q5 [Direct mapping] Endoplasmic reticulum-Golgi intermediate compartment protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		105 aa 11.7 kDa	No	0
ERGIC1-013 ENSP00000427713 ENST00000523291	F2Z2U2 [Direct mapping] Endoplasmic reticulum-Golgi intermediate compartment protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	138 aa 15.6 kDa	No	1