Cell atlas - GRK7 - The Human Protein Atlas

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GRK7

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	GRK7
Gene description	G protein-coupled receptor kinase 7
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	GRK7 (HGNC Symbol)
Synonyms	GPRK7
Description	G protein-coupled receptor kinase 7 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008]
Chromosome	3
Cytoband	q23
Chromosome location (bp)	141778148 - 141818490
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000114124 (version 83.38)
Entrez gene	131890
UniProt	Q8WTQ7 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WTQ7
Antibodypedia	GRK7 antibodies

PROTEIN BROWSER

GRK7-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GRK7-001 ENSP00000264952 ENST00000264952	Q8WTQ7 [Direct mapping] G protein-coupled receptor kinase 7 Show all	Enzymes ENZYME proteins Transferases Kinases AGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004703 [G-protein coupled receptor kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0007601 [visual perception] GO:0007603 [phototransduction, visible light] GO:0016056 [rhodopsin mediated signaling pathway] GO:0022400 [regulation of rhodopsin mediated signaling pathway] GO:0046777 [protein autophosphorylation] GO:0050254 [rhodopsin kinase activity] GO:0097381 [photoreceptor disc membrane] Show all	553 aa 62.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.