Tissue expression of FRMD4B - Summary - The Human Protein Atlas

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FRMD4B

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA
MOUSE BRAIN

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	FRMD4B
Gene description	FERM domain containing 4B
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Mixed
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA009705
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	FRMD4B (HGNC Symbol)
Synonyms	GRSP1, KIAA1013
Description	FERM domain containing 4B (HGNC Symbol)
Entrez gene summary	This gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled coil domains. This protein may play a role as a scaffolding protein. [provided by RefSeq, Mar 2014]
Chromosome	3
Cytoband	p14.1
Chromosome location (bp)	69169990 - 69542583
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000114541 (version 83.38)
Entrez gene	23150
UniProt	Q9Y2L6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2L6
Antibodypedia	FRMD4B antibodies

PROTEIN BROWSER

FRMD4B-001	FRMD4B-005	FRMD4B-006	FRMD4B-007	FRMD4B-011	FRMD4B-013	FRMD4B-014	FRMD4B-017	FRMD4B-019

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FRMD4B-001 ENSP00000381549 ENST00000398540	Q9Y2L6 [Direct mapping] FERM domain-containing protein 4B Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] GO:0090162 [establishment of epithelial cell polarity] Show all	1034 aa 118 kDa	No	0
FRMD4B-005 ENSP00000418682 ENST00000478263	E9PGA7 [Direct mapping] FERM domain-containing protein 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		686 aa 77.3 kDa	No	0
FRMD4B-006 ENSP00000417765 ENST00000497880	C9J7M5 [Direct mapping] FERM domain-containing protein 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005856 [cytoskeleton] Show all	80 aa 9.5 kDa	No	0
FRMD4B-007 ENSP00000417550 ENST00000459638	C9JA15 [Direct mapping] FERM domain-containing protein 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005856 [cytoskeleton] Show all	113 aa 13.3 kDa	No	0
FRMD4B-011 ENSP00000418023 ENST00000460709	C9JAW0 [Direct mapping] FERM domain-containing protein 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005856 [cytoskeleton] Show all	142 aa 16.5 kDa	No	0
FRMD4B-013 ENSP00000418373 ENST00000473029	C9J6Q2 [Direct mapping] FERM domain-containing protein 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005856 [cytoskeleton] Show all	167 aa 19.3 kDa	No	0
FRMD4B-014 ENSP00000418962 ENST00000493880	H7C550 [Direct mapping] FERM domain-containing protein 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005856 [cytoskeleton] Show all	183 aa 21 kDa	No	0
FRMD4B-017 ENSP00000419869 ENST00000462512	C9JYK2 [Direct mapping] FERM domain-containing protein 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005856 [cytoskeleton] Show all	161 aa 18.8 kDa	No	0
FRMD4B-019 ENSP00000420735 ENST00000489817	C9JBX2 [Direct mapping] FERM domain-containing protein 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		17 aa 2.1 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.