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GORASP1

GENERAL INFORMATION

Gene name

 GORASP1

Gene description

 Golgi reassembly stacking protein 1, 65kDa

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression with a granular pattern in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA056283
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Appendix
N/A
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical
N/ACerebral cortexHippocampusCaudateCerebellumThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleNasopharynxBronchusLungLiverGallbladderPancreasOral mucosaSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSoft tissueSkinNotdetectedLowMediumHighSCORE

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
Cerebral cortexThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSkin010203040TPM
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
HypothalamusPituitary glandCerebral cortexHippocampusCaudateCerebellumThyroid glandAdrenal glandSpleenHeart muscleSkeletal muscleLungLiverPancreasSalivary glandEsophagusStomachSmall intestineColonKidneyUrinary bladderTestisProstateBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryAdipose tissueSkin02468101214RPKM
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
Pituitary glandBrainHippocampusCaudateCerebellumThyroid glandAppendixLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusSmall intestineColonKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumOvaryPlacentaAdipose tissueRetina01020304050Tags Per Million

GENE INFORMATION

Gene name

 GORASP1 (HGNC Symbol)

Synonyms

 FLJ23443, GOLPH5, GRASP65, P65

Description

 Golgi reassembly stacking protein 1, 65kDa (HGNC Symbol)

Entrez gene summary

 The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Chromosome

 3

Cytoband

 p22.2

Chromosome location (bp)

 39096659 - 39108363

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000114745 (version 83.38)

Entrez gene

 64689

UniProt

 Q9BQQ3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BQQ3

Antibodypedia

 GORASP1 antibodies

PROTEIN BROWSER
GORASP1-001
GORASP1-002
GORASP1-004
GORASP1-009
GORASP1-021
GORASP1-022

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GORASP1-001
ENSP00000313869
ENST00000319283
Q9BQQ3 [Direct mapping]
Golgi reassembly-stacking protein 1
A0A024R2U5 [Target identity:100%; Query identity:100%]
Golgi reassembly stacking protein 1, 65kDa, isoform CRA_c
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0000278 [mitotic cell cycle]
GO:0005515 [protein binding]
GO:0005794 [Golgi apparatus]
GO:0006487 [protein N-linked glycosylation]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0007030 [Golgi organization]
GO:0015031 [protein transport]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0050774 [negative regulation of dendrite morphogenesis]
GO:0061024 [membrane organization]
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 440 aa
46.5 kDa 		No 0
GORASP1-002
ENSP00000419123
ENST00000479927
B4E1H8 [Direct mapping]
Golgi reassembly-stacking protein 1; cDNA FLJ58222, highly similar to Golgi reassembly-stacking protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005794 [Golgi apparatus]
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 345 aa
35.7 kDa 		No 0
GORASP1-004
ENSP00000395709
ENST00000422110
B3KPY8 [Direct mapping]
Golgi reassembly stacking protein 1, 65kDa, isoform CRA_f; Golgi reassembly-stacking protein 1; cDNA FLJ32481 fis, clone SKNMC2001113, moderately similar to Golgi reassembly-stacking protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005794 [Golgi apparatus]
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 285 aa
29.2 kDa 		No 0
GORASP1-009
ENSP00000411104
ENST00000441081
C9J9V9 [Direct mapping]
Golgi reassembly-stacking protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
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 89 aa
9.8 kDa 		No 0
GORASP1-021
ENSP00000392993
ENST00000437458
C9J0V5 [Direct mapping]
Golgi reassembly-stacking protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
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 193 aa
21.6 kDa 		No 0
GORASP1-022
ENSP00000405976
ENST00000416741
C9J5S6 [Direct mapping]
Golgi reassembly-stacking protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 70 aa
7.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.