Expression of MOB1A in cancer - Summary

CANCER ATLAS

Gene description

MOB kinase activator 1A

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA047088

GENE INFORMATION
Gene name	MOB1A (HGNC Symbol)
Synonyms	C2orf6, FLJ10788, FLJ11595, Mats1, MOB1, Mob4B, MOBK1B, MOBKL1B
Description	MOB kinase activator 1A (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Chromosome	2
Cytoband	p13.1
Chromosome location (bp)	74152528 - 74178898
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000114978 (version 83.38)
Entrez gene	55233
UniProt	Q9H8S9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H8S9
Antibodypedia	MOB1A antibodies

PROTEIN BROWSER

MOB1A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MOB1A-001 ENSP00000379364 ENST00000396049	Q9H8S9 [Direct mapping] MOB kinase activator 1A Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0035329 [hippo signaling] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	216 aa 25.1 kDa	No	0