Expression of SLC30A3 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 30 (zinc transporter), member 3

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA060505

GENE INFORMATION
Gene name	SLC30A3 (HGNC Symbol)
Synonyms	ZNT3
Description	Solute carrier family 30 (zinc transporter), member 3 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p23.3
Chromosome location (bp)	27253684 - 27275817
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115194 (version 83.38)
Entrez gene	7781
UniProt	Q99726 (UniProt - Evidence at protein level)
neXtProt	NX_Q99726
Antibodypedia	SLC30A3 antibodies

PROTEIN BROWSER

SLC30A3-001	SLC30A3-002	SLC30A3-003	SLC30A3-004	SLC30A3-005	SLC30A3-006	SLC30A3-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC30A3-001 ENSP00000233535 ENST00000233535	Q99726 [Direct mapping] Zinc transporter 3 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005765 [lysosomal membrane] GO:0005768 [endosome] GO:0005770 [late endosome] GO:0005887 [integral component of plasma membrane] GO:0006810 [transport] GO:0006812 [cation transport] GO:0008021 [synaptic vesicle] GO:0008324 [cation transmembrane transporter activity] GO:0010043 [response to zinc ion] GO:0015633 [zinc transporting ATPase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0030672 [synaptic vesicle membrane] GO:0031902 [late endosome membrane] GO:0043005 [neuron projection] GO:0051050 [positive regulation of transport] GO:0055085 [transmembrane transport] GO:0061088 [regulation of sequestering of zinc ion] GO:0071577 [zinc II ion transmembrane transport] Show all	388 aa 41.9 kDa	No	5
SLC30A3-002 ENSP00000388219 ENST00000445870	H7BZ83 [Direct mapping] Zinc transporter 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0008324 [cation transmembrane transporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:0098655 [cation transmembrane transport] Show all	302 aa 32.7 kDa	No	2
SLC30A3-003 ENSP00000403912 ENST00000450118	C9JHZ9 [Direct mapping] Zinc transporter 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0008324 [cation transmembrane transporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:0098655 [cation transmembrane transport] Show all	111 aa 12.1 kDa	No	3
SLC30A3-004 ENSP00000403959 ENST00000424577	C9JHX4 [Direct mapping] Zinc transporter 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0008324 [cation transmembrane transporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:0098655 [cation transmembrane transport] Show all	170 aa 18.6 kDa	No	3
SLC30A3-005 ENSP00000414320 ENST00000432351	C9JM13 [Direct mapping] Zinc transporter 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0008324 [cation transmembrane transporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:0098655 [cation transmembrane transport] Show all	240 aa 25.9 kDa	No	6
SLC30A3-006 ENSP00000392673 ENST00000426569	C9J1K4 [Direct mapping] Zinc transporter 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0008324 [cation transmembrane transporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:0098655 [cation transmembrane transport] Show all	99 aa 10.8 kDa	No	3
SLC30A3-007 ENSP00000393545 ENST00000426924	C9JV68 [Direct mapping] Zinc transporter 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0008324 [cation transmembrane transporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:0098655 [cation transmembrane transport] Show all	230 aa 24.8 kDa	No	4