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PCGF1

CANCER ATLAS

Gene description

 Polycomb group ring finger 1

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA011356

GENE INFORMATION

Gene name

 PCGF1 (HGNC Symbol)

Synonyms

 MGC10882, NSPC1, RNF68

Description

 Polycomb group ring finger 1 (HGNC Symbol)

Entrez gene summary

 PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM, Aug 2008]

Chromosome

 2

Cytoband

 p13.1

Chromosome location (bp)

 74505043 - 74508580

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000115289 (version 83.38)

Entrez gene

 84759

UniProt

 Q9BSM1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BSM1

Antibodypedia

 PCGF1 antibodies

PROTEIN BROWSER
PCGF1-001
PCGF1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PCGF1-001
ENSP00000233630
ENST00000233630
Q9BSM1 [Direct mapping]
Polycomb group RING finger protein 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008022 [protein C-terminus binding]
GO:0008270 [zinc ion binding]
GO:0031519 [PcG protein complex]
GO:0035518 [histone H2A monoubiquitination]
GO:0046872 [metal ion binding]
Show all
 259 aa
30.3 kDa 		No 0
PCGF1-201
ENSP00000478746
ENST00000612049
A0A087WUL5 [Direct mapping]
Polycomb group RING finger protein 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0008270 [zinc ion binding]
GO:0046872 [metal ion binding]
Show all
 237 aa
27.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.