Expression of UNC50 in cancer - Summary - The Human Protein Atlas

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UNC50

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Unc-50 homolog (C. elegans)

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA027009

GENE INFORMATION
Gene name	UNC50 (HGNC Symbol)
Synonyms	GMH1, UNCL, URP
Description	Unc-50 homolog (C. elegans) (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q11.2
Chromosome location (bp)	98608579 - 98618515
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115446 (version 83.38)
Entrez gene	25972
UniProt	Q53HI1 (UniProt - Evidence at protein level)
neXtProt	NX_Q53HI1
Antibodypedia	UNC50 antibodies

PROTEIN BROWSER

UNC50-001	UNC50-002	UNC50-003	UNC50-004	UNC50-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UNC50-001 ENSP00000350409 ENST00000357765	Q53HI1 [Direct mapping] Protein unc-50 homolog Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003723 [RNA binding] GO:0005637 [nuclear inner membrane] GO:0005794 [Golgi apparatus] GO:0006810 [transport] GO:0007166 [cell surface receptor signaling pathway] GO:0015031 [protein transport] GO:0030173 [integral component of Golgi membrane] Show all	259 aa 30.4 kDa	No	5
UNC50-002 ENSP00000387146 ENST00000409975	J3KQ47 [Direct mapping] Protein unc-50 homolog Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0030173 [integral component of Golgi membrane] Show all	276 aa 32.4 kDa	No	6
UNC50-003 ENSP00000386466 ENST00000409347	J3KQ47 [Direct mapping] Protein unc-50 homolog Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0030173 [integral component of Golgi membrane] Show all	276 aa 32.4 kDa	No	6
UNC50-004 ENSP00000377131 ENST00000393493	H7BYK3 [Direct mapping] Protein unc-50 homolog Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0030173 [integral component of Golgi membrane] Show all	128 aa 14.8 kDa	No	3
UNC50-005 ENSP00000412224 ENST00000423713	H7C3J5 [Direct mapping] Protein unc-50 homolog Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0030173 [integral component of Golgi membrane] Show all	92 aa 10.9 kDa	No	2

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.