Tissue expression of KCNJ13 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	KCNJ13
Gene description	Potassium channel, inwardly rectifying subfamily J, member 13
Protein class	Disease related genes Potential drug targets Predicted membrane proteins Transporters Voltage-gated ion channels
Predicted localization	Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (small intestine, parathyroid gland)
FANTOM5:	Group enriched (retina, small intestine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (small intestine, parathyroid gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (retina, small intestine)

GENE INFORMATION
Gene name	KCNJ13 (HGNC Symbol)
Synonyms	Kir1.4, Kir7.1, LCA16
Description	Potassium channel, inwardly rectifying subfamily J, member 13 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the inwardly rectifying potassium channel family of proteins. Members of this family form ion channel pores that allow potassium ions to pass into a cell. The encoded protein belongs to a subfamily of low signal channel conductance proteins that have a low dependence on potassium concentration. Mutations in this gene are associated with snowflake vitreoretinal degeneration. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Chromosome	2
Cytoband	q37.1
Chromosome location (bp)	232766464 - 232776568
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115474 (version 83.38)
Entrez gene	3769
UniProt	O60928 (UniProt - Evidence at protein level)
neXtProt	NX_O60928
Antibodypedia	KCNJ13 antibodies

PROTEIN BROWSER

KCNJ13-001	KCNJ13-002	KCNJ13-003	KCNJ13-004	KCNJ13-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KCNJ13-001 ENSP00000233826 ENST00000233826	O60928 [Direct mapping] Inward rectifier potassium channel 13 Show all	Transporters Transporter channels and pores Voltage-gated ion channels Inwardly Rectifying Potassium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Show all	GO:0005242 [inward rectifier potassium channel activity] GO:0005887 [integral component of plasma membrane] GO:0006813 [potassium ion transport] GO:0010107 [potassium ion import] GO:0016021 [integral component of membrane] GO:0034765 [regulation of ion transmembrane transport] Show all	360 aa 40.5 kDa	No	2
KCNJ13-002 ENSP00000386251 ENST00000410029	O60928 [Direct mapping] Inward rectifier potassium channel 13 Show all	Transporters Transporter channels and pores Voltage-gated ion channels Inwardly Rectifying Potassium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0005242 [inward rectifier potassium channel activity] GO:0005887 [integral component of plasma membrane] GO:0006813 [potassium ion transport] GO:0010107 [potassium ion import] GO:0016021 [integral component of membrane] GO:0034765 [regulation of ion transmembrane transport] Show all	360 aa 40.5 kDa	No	2
KCNJ13-003 ENSP00000386408 ENST00000409779	O60928 [Direct mapping] Inward rectifier potassium channel 13 Show all	Transporters Transporter channels and pores Voltage-gated ion channels Inwardly Rectifying Potassium Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Show all	GO:0005242 [inward rectifier potassium channel activity] GO:0005887 [integral component of plasma membrane] GO:0006813 [potassium ion transport] GO:0010107 [potassium ion import] GO:0016021 [integral component of membrane] GO:0034765 [regulation of ion transmembrane transport] Show all	94 aa 11 kDa	No	1
KCNJ13-004 ENSP00000407284 ENST00000438786	C9JWD6 [Direct mapping] Inward rectifier potassium channel 13 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005242 [inward rectifier potassium channel activity] GO:0005887 [integral component of plasma membrane] GO:0006813 [potassium ion transport] GO:0010107 [potassium ion import] GO:0016021 [integral component of membrane] GO:0034765 [regulation of ion transmembrane transport] Show all	184 aa 20.3 kDa	No	1
KCNJ13-005 ENSP00000416896 ENST00000444142	H7C4D1 [Direct mapping] Inward rectifier potassium channel 13 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0005242 [inward rectifier potassium channel activity] GO:0005887 [integral component of plasma membrane] GO:0006813 [potassium ion transport] GO:0010107 [potassium ion import] GO:0016021 [integral component of membrane] GO:0034765 [regulation of ion transmembrane transport] Show all	137 aa 15.4 kDa	No	2