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KDM3A

GENERAL INFORMATION

Gene name

 KDM3A

Gene description

 Lysine (K)-specific demethylase 3A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 6
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 KDM3A (HGNC Symbol)

Synonyms

 JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA

Description

 Lysine (K)-specific demethylase 3A (HGNC Symbol)

Entrez gene summary

 This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Chromosome

 2

Cytoband

 p11.2

Chromosome location (bp)

 86440647 - 86492716

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000115548 (version 83.38)

Entrez gene

 55818

UniProt

 Q9Y4C1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y4C1

Antibodypedia

 KDM3A antibodies

PROTEIN BROWSER
KDM3A-001
KDM3A-002
KDM3A-006
KDM3A-008
KDM3A-201
KDM3A-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KDM3A-001
ENSP00000386660
ENST00000409556
Q9Y4C1 [Direct mapping]
Lysine-specific demethylase 3A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001047 [core promoter binding]
GO:0001666 [response to hypoxia]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005506 [iron ion binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0007283 [spermatogenesis]
GO:0007290 [spermatid nucleus elongation]
GO:0008584 [male gonad development]
GO:0009755 [hormone-mediated signaling pathway]
GO:0010468 [regulation of gene expression]
GO:0010628 [positive regulation of gene expression]
GO:0016020 [membrane]
GO:0030521 [androgen receptor signaling pathway]
GO:0033169 [histone H3-K9 demethylation]
GO:0036123 [histone H3-K9 dimethylation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046293 [formaldehyde biosynthetic process]
GO:0050681 [androgen receptor binding]
GO:0051213 [dioxygenase activity]
GO:0051573 [negative regulation of histone H3-K9 methylation]
GO:0055114 [oxidation-reduction process]
GO:2000036 [regulation of stem cell population maintenance]
GO:2000736 [regulation of stem cell differentiation]
Show all
 1321 aa
147.3 kDa 		No 0
KDM3A-002
ENSP00000386516
ENST00000409064
Q9Y4C1 [Direct mapping]
Lysine-specific demethylase 3A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005506 [iron ion binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0009755 [hormone-mediated signaling pathway]
GO:0016020 [membrane]
GO:0030521 [androgen receptor signaling pathway]
GO:0033169 [histone H3-K9 demethylation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046293 [formaldehyde biosynthetic process]
GO:0050681 [androgen receptor binding]
GO:0051213 [dioxygenase activity]
GO:0055114 [oxidation-reduction process]
Show all
 1321 aa
147.3 kDa 		No 0
KDM3A-006
ENSP00000397660
ENST00000427678
C9J7Q7 [Direct mapping]
Lysine-specific demethylase 3A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 170 aa
19.4 kDa 		No 0
KDM3A-008
ENSP00000396561
ENST00000452034
C9JC73 [Direct mapping]
Lysine-specific demethylase 3A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 121 aa
14 kDa 		No 0
KDM3A-201
ENSP00000323659
ENST00000312912
Q9Y4C1 [Direct mapping]
Lysine-specific demethylase 3A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005506 [iron ion binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0009755 [hormone-mediated signaling pathway]
GO:0016020 [membrane]
GO:0030521 [androgen receptor signaling pathway]
GO:0033169 [histone H3-K9 demethylation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046293 [formaldehyde biosynthetic process]
GO:0050681 [androgen receptor binding]
GO:0051213 [dioxygenase activity]
GO:0055114 [oxidation-reduction process]
Show all
 1321 aa
147.3 kDa 		No 0
KDM3A-202
ENSP00000438324
ENST00000542128
F5H070 [Direct mapping]
Lysine-specific demethylase 3A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
Show all
 1327 aa
148.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.