Cell atlas - ZNF142 - The Human Protein Atlas

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ZNF142

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli fibrillar center
	Nucleus

Human cell
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF142
Gene description	Zinc finger protein 142
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli (fibrillar center). In addition localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli fibrillar center (approved)
Additional location	In addition localized to the Nucleus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA049594
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli (fibrillar center). In addition localized to the nucleus.

Main location

Nucleoli fibrillar center (approved)

Additional location

Nucleus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA049594	HeLa	Nucleus
	HPA049594	HeLa	Nucleoli fibrillar center
	HPA049594	U-2 OS	Nucleoli fibrillar center
	HPA049594	U-251 MG	Nucleus
	HPA049594	U-251 MG	Nucleoli fibrillar center

GENE INFORMATION
Gene name	ZNF142 (HGNC Symbol)
Synonyms	KIAA0236, pHZ-49
Description	Zinc finger protein 142 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins. It contains 31 C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]
Chromosome	2
Cytoband	q35
Chromosome location (bp)	218637916 - 218659655
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115568 (version 83.38)
Entrez gene	7701
UniProt	P52746 (UniProt - Evidence at protein level)
neXtProt	NX_P52746
Antibodypedia	ZNF142 antibodies

PROTEIN BROWSER

ZNF142-001	ZNF142-006	ZNF142-007	ZNF142-008	ZNF142-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF142-001 ENSP00000408643 ENST00000449707	P52746 [Direct mapping] Zinc finger protein 142 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003677 [DNA binding] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008150 [biological_process] GO:0046872 [metal ion binding] Show all	1687 aa 187.9 kDa	No	0
ZNF142-006 ENSP00000391599 ENST00000432460	C9JBL7 [Direct mapping] Zinc finger protein 142 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		14 aa 1.5 kDa	No	0
ZNF142-007 ENSP00000400424 ENST00000450560	C9J055 [Direct mapping] Zinc finger protein 142 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		26 aa 2.7 kDa	No	0
ZNF142-008 ENSP00000415156 ENST00000440934	H7C414 [Direct mapping] Zinc finger protein 142 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	294 aa 31.3 kDa	No	0
ZNF142-201 ENSP00000398798 ENST00000411696	P52746 [Direct mapping] Zinc finger protein 142 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003677 [DNA binding] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008150 [biological_process] GO:0046872 [metal ion binding] Show all	1687 aa 187.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.