Tissue expression of TAF1B - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	TAF1B
Gene description	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	TAF1B (HGNC Symbol)
Synonyms	RAF1B, RAFI63, SL1, TAFI63
Description	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa (HGNC Symbol)
Entrez gene summary	Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	p25.1
Chromosome location (bp)	9843354 - 9934416
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115750 (version 83.38)
Entrez gene	9014
UniProt	Q53T94 (UniProt - Evidence at protein level)
neXtProt	NX_Q53T94
Antibodypedia	TAF1B antibodies

PROTEIN BROWSER

TAF1B-001	TAF1B-010	TAF1B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TAF1B-001 ENSP00000263663 ENST00000263663	Q53T94 [Direct mapping] TATA box-binding protein-associated factor RNA polymerase I subunit B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000183 [chromatin silencing at rDNA] GO:0001164 [RNA polymerase I CORE element sequence-specific DNA binding] GO:0001187 [transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting] GO:0001189 [RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005668 [RNA polymerase transcription factor SL1 complex] GO:0006351 [transcription, DNA-templated] GO:0006360 [transcription from RNA polymerase I promoter] GO:0006361 [transcription initiation from RNA polymerase I promoter] GO:0006362 [transcription elongation from RNA polymerase I promoter] GO:0006363 [termination of RNA polymerase I transcription] GO:0010467 [gene expression] GO:0017025 [TBP-class protein binding] GO:0040029 [regulation of gene expression, epigenetic] GO:0045814 [negative regulation of gene expression, epigenetic] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] GO:0070860 [RNA polymerase I core factor complex] Show all	588 aa 68.8 kDa	No	1
TAF1B-010 ENSP00000475608 ENST00000492648	U3KQ75 [Direct mapping] TATA box-binding protein-associated factor RNA polymerase I subunit B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		216 aa 25.4 kDa	No	2
TAF1B-201 ENSP00000486572 ENST00000625239	F8WDU0 [Direct mapping] TATA box-binding protein-associated factor RNA polymerase I subunit B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		57 aa 6.6 kDa	No	0