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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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SLC1A4
  • TISSUE

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

SLC1A4

Gene description

Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4

Protein class

Plasma proteins
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression, often with a membranous pattern.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Approved based on 1 antibody.
HPA034964
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

SLC1A4 (HGNC Symbol)

Synonyms

ASCT1, SATT

Description

Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 (HGNC Symbol)

Entrez gene summary

Chromosome

2

Cytoband

p14

Chromosome location (bp)

64988477 - 65023865

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115902 (version 83.38)

Entrez gene

6509

UniProt

P43007 (UniProt - Evidence at protein level)

neXtProt

NX_P43007

Antibodypedia

SLC1A4 antibodies

PROTEIN BROWSER

SLC1A4-001
SLC1A4-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC1A4-001
ENSP00000234256
ENST00000234256
P43007 [Direct mapping]
Neutral amino acid transporter A
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005254 [chloride channel activity]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005882 [intermediate filament]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006821 [chloride transport]
GO:0006835 [dicarboxylic acid transport]
GO:0006865 [amino acid transport]
GO:0006868 [glutamine transport]
GO:0009986 [cell surface]
GO:0015175 [neutral amino acid transmembrane transporter activity]
GO:0015180 [L-alanine transmembrane transporter activity]
GO:0015184 [L-cystine transmembrane transporter activity]
GO:0015186 [L-glutamine transmembrane transporter activity]
GO:0015193 [L-proline transmembrane transporter activity]
GO:0015194 [L-serine transmembrane transporter activity]
GO:0015195 [L-threonine transmembrane transporter activity]
GO:0015808 [L-alanine transport]
GO:0015811 [L-cystine transport]
GO:0015824 [proline transport]
GO:0015825 [L-serine transport]
GO:0015826 [threonine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0017153 [sodium:dicarboxylate symporter activity]
GO:0030425 [dendrite]
GO:0034589 [hydroxyproline transport]
GO:0034590 [L-hydroxyproline transmembrane transporter activity]
GO:0035249 [synaptic transmission, glutamatergic]
GO:0035524 [proline transmembrane transport]
GO:0042470 [melanosome]
GO:0043025 [neuronal cell body]
GO:0050890 [cognition]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0098779 [mitophagy in response to mitochondrial depolarization]
GO:1902476 [chloride transmembrane transport]
Show all
532 aa
55.7 kDa
No 9
SLC1A4-005
ENSP00000431942
ENST00000531327
P43007 [Direct mapping]
Neutral amino acid transporter A
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005254 [chloride channel activity]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005882 [intermediate filament]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006821 [chloride transport]
GO:0006835 [dicarboxylic acid transport]
GO:0006865 [amino acid transport]
GO:0006868 [glutamine transport]
GO:0009986 [cell surface]
GO:0015180 [L-alanine transmembrane transporter activity]
GO:0015184 [L-cystine transmembrane transporter activity]
GO:0015186 [L-glutamine transmembrane transporter activity]
GO:0015193 [L-proline transmembrane transporter activity]
GO:0015194 [L-serine transmembrane transporter activity]
GO:0015195 [L-threonine transmembrane transporter activity]
GO:0015808 [L-alanine transport]
GO:0015811 [L-cystine transport]
GO:0015824 [proline transport]
GO:0015825 [L-serine transport]
GO:0015826 [threonine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0017153 [sodium:dicarboxylate symporter activity]
GO:0034589 [hydroxyproline transport]
GO:0034590 [L-hydroxyproline transmembrane transporter activity]
GO:0035249 [synaptic transmission, glutamatergic]
GO:0035524 [proline transmembrane transport]
GO:0042470 [melanosome]
GO:0050890 [cognition]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0098779 [mitophagy in response to mitochondrial depolarization]
GO:1902476 [chloride transmembrane transport]
Show all
234 aa
24.6 kDa
Yes 3

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