Cell atlas - THADA - The Human Protein Atlas

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THADA

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	THADA
Gene description	Thyroid adenoma associated
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA035191
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA035191	A-431	Cytosol
	HPA035191	U-2 OS	Cytosol
	HPA035191	U-251 MG	Cytosol

GENE INFORMATION
Gene name	THADA (HGNC Symbol)
Synonyms	FLJ21877, GITA, KIAA1767
Description	Thyroid adenoma associated (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p21
Chromosome location (bp)	43230836 - 43596046
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115970 (version 83.38)
Entrez gene	63892
UniProt	Q6YHU6 (UniProt - Evidence at protein level)
neXtProt	NX_Q6YHU6
Antibodypedia	THADA antibodies

PROTEIN BROWSER

THADA-001	THADA-002	THADA-004	THADA-005	THADA-007	THADA-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
THADA-001 ENSP00000386088 ENST00000405975	Q6YHU6 [Direct mapping] Thyroid adenoma-associated protein Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005515 [protein binding] Show all	1953 aa 219.6 kDa	No	0
THADA-002 ENSP00000385995 ENST00000405006	Q6YHU6 [Direct mapping] Thyroid adenoma-associated protein Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005515 [protein binding] Show all	1953 aa 219.6 kDa	No	0
THADA-004 ENSP00000384266 ENST00000404790	Q6YHU6 [Direct mapping] Thyroid adenoma-associated protein Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005515 [protein binding] Show all	894 aa 100.7 kDa	No	0
THADA-005 ENSP00000385469 ENST00000403856	B5MC89 [Direct mapping] Thyroid adenoma-associated protein Show all	Phobius predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0016021 [integral component of membrane] Show all	870 aa 98.4 kDa	No	0
THADA-007 ENSP00000385441 ENST00000402360	Q6YHU6 [Direct mapping] Thyroid adenoma-associated protein Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005515 [protein binding] Show all	937 aa 105.4 kDa	No	0
THADA-009 ENSP00000386112 ENST00000407351	H0Y3V5 [Direct mapping] Thyroid adenoma-associated protein Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] Show all	1193 aa 133.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.