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BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]
Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005801 [cis-Golgi network] GO:0008013 [beta-catenin binding] GO:0014908 [myotube differentiation involved in skeletal muscle regeneration] GO:0035019 [somatic stem cell population maintenance] GO:0035914 [skeletal muscle cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0060070 [canonical Wnt signaling pathway]
A0A087WVU5 [Direct mapping] B-cell CLL/lymphoma 9 protein
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014)
