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AGMAT

GENERAL INFORMATION

Gene name

 AGMAT

Gene description

 Agmatine ureohydrolase (agmatinase)

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (kidney)
GTEx:Tissue enhanced (kidney, liver)
FANTOM5:Group enriched (liver, small intestine, kidney, colon)

Protein evidence

 Evidence at protein level

Protein expression

 High cytoplasmic expression in the GI-tract and renal tubules.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA026443 , HPA028321
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (kidney)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (kidney, liver)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (liver, small intestine, kidney, colon)

GENE INFORMATION

Gene name

 AGMAT (HGNC Symbol)

Synonyms

 FLJ23384

Description

 Agmatine ureohydrolase (agmatinase) (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p36.21

Chromosome location (bp)

 15572353 - 15585110

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000116771 (version 83.38)

Entrez gene

 79814

UniProt

 Q9BSE5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BSE5

Antibodypedia

 AGMAT antibodies

PROTEIN BROWSER
AGMAT-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AGMAT-001
ENSP00000364986
ENST00000375826
Q9BSE5 [Direct mapping]
Agmatinase, mitochondrial
A0A024QZ78 [Target identity:100%; Query identity:100%]
Agmatine ureohydrolase (Agmatinase), isoform CRA_a
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Enzymes
   ENZYME proteins
   Hydrolases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005739 [mitochondrion]
GO:0006595 [polyamine metabolic process]
GO:0008295 [spermidine biosynthetic process]
GO:0008783 [agmatinase activity]
GO:0016813 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines]
GO:0033388 [putrescine biosynthetic process from arginine]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
GO:0097055 [agmatine biosynthetic process]
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 352 aa
37.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.