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ZBTB17

CANCER ATLAS

Gene description

 Zinc finger and BTB domain containing 17

Protein class

 Predicted intracellular proteins, Transcription factors

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA005789

GENE INFORMATION

Gene name

 ZBTB17 (HGNC Symbol)

Synonyms

 MIZ1, pHZ-67, ZNF151, ZNF60

Description

 Zinc finger and BTB domain containing 17 (HGNC Symbol)

Entrez gene summary

 This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18. [provided by RefSeq, Jul 2008]

Chromosome

 1

Cytoband

 p36.13

Chromosome location (bp)

 15941869 - 15976132

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000116809 (version 83.38)

Entrez gene

 7709

UniProt

 Q13105 (UniProt - Evidence at protein level)

neXtProt

 NX_Q13105

Antibodypedia

 ZBTB17 antibodies

PROTEIN BROWSER
ZBTB17-001
ZBTB17-007
ZBTB17-013
ZBTB17-015
ZBTB17-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZBTB17-001
ENSP00000364895
ENST00000375743
Q13105 [Direct mapping]
Zinc finger and BTB domain-containing protein 17
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0030968 [endoplasmic reticulum unfolded protein response]
GO:0036498 [IRE1-mediated unfolded protein response]
GO:0044267 [cellular protein metabolic process]
GO:0045786 [negative regulation of cell cycle]
GO:0046872 [metal ion binding]
GO:1903146 [regulation of mitophagy]
GO:1903955 [positive regulation of protein targeting to mitochondrion]
Show all
 803 aa
87.9 kDa 		No 0
ZBTB17-007
ENSP00000408483
ENST00000444358
H0Y6X2 [Direct mapping]
Zinc finger and BTB domain-containing protein 17
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0046872 [metal ion binding]
Show all
 241 aa
26.6 kDa 		No 0
ZBTB17-013
ENSP00000400827
ENST00000440560
H7C1K8 [Direct mapping]
Zinc finger and BTB domain-containing protein 17
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0046872 [metal ion binding]
Show all
 210 aa
22.2 kDa 		No 0
ZBTB17-015
ENSP00000438529
ENST00000537142
Q13105 [Direct mapping]
Zinc finger and BTB domain-containing protein 17
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0030968 [endoplasmic reticulum unfolded protein response]
GO:0036498 [IRE1-mediated unfolded protein response]
GO:0044267 [cellular protein metabolic process]
GO:0045786 [negative regulation of cell cycle]
GO:0046872 [metal ion binding]
GO:1903146 [regulation of mitophagy]
GO:1903955 [positive regulation of protein targeting to mitochondrion]
Show all
 721 aa
79.2 kDa 		No 0
ZBTB17-201
ENSP00000364885
ENST00000375733
Q13105 [Direct mapping]
Zinc finger and BTB domain-containing protein 17
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001702 [gastrulation with mouth forming second]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007398 [ectoderm development]
GO:0030968 [endoplasmic reticulum unfolded protein response]
GO:0036498 [IRE1-mediated unfolded protein response]
GO:0044267 [cellular protein metabolic process]
GO:0045786 [negative regulation of cell cycle]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:1903146 [regulation of mitophagy]
GO:1903955 [positive regulation of protein targeting to mitochondrion]
Show all
 810 aa
88.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.