Expression of ADPRHL2 in cancer - Summary - The Human Protein Atlas

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ADPRHL2

TISSUE

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CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

ADP-ribosylhydrolase like 2

Protein class

Enzymes, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA027104	HPA027141

GENE INFORMATION
Gene name	ADPRHL2 (HGNC Symbol)
Synonyms	ARH3, FLJ20446
Description	ADP-ribosylhydrolase like 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm.[provided by RefSeq, Feb 2009]
Chromosome	1
Cytoband	p34.3
Chromosome location (bp)	36088875 - 36093932
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000116863 (version 83.38)
Entrez gene	54936
UniProt	Q9NX46 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NX46
Antibodypedia	ADPRHL2 antibodies

PROTEIN BROWSER

ADPRHL2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADPRHL2-001 ENSP00000362273 ENST00000373178	Q9NX46 [Direct mapping] Poly(ADP-ribose) glycohydrolase ARH3 Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004649 [poly(ADP-ribose) glycohydrolase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0008152 [metabolic process] GO:0046872 [metal ion binding] GO:0071451 [cellular response to superoxide] Show all	363 aa 38.9 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.