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Moderate nuclear staining was observed in most malignant cells. Malignant gliomas were strongly stained. A majority of malignant lymphomas, ovarian, prostate and cervical cancers were weakly stained or negative.
GENE INFORMATION
Gene name
GBP3 (HGNC Symbol)
Synonyms
FLJ10961
Description
Guanylate binding protein 3 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. [provided by RefSeq, Jul 2008]