Tissue expression of ERI3 - Summary - The Human Protein Atlas

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ERI3

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ERI3
Gene description	ERI1 exoribonuclease family member 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous cytoplasmic and nuclear expression, most abundant in glandular cells.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA027147 , HPA029895
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ERI3 (HGNC Symbol)
Synonyms	FLJ22943, PINT1, PRNPIP
Description	ERI1 exoribonuclease family member 3 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p34.1
Chromosome location (bp)	44221070 - 44355260
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000117419 (version 83.38)
Entrez gene	79033
UniProt	O43414 (UniProt - Evidence at protein level)
neXtProt	NX_O43414
Antibodypedia	ERI3 antibodies

PROTEIN BROWSER

ERI3-001	ERI3-002	ERI3-003	ERI3-004	ERI3-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ERI3-001 ENSP00000361331 ENST00000372257	O43414 [Direct mapping] ERI1 exoribonuclease 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000175 [3'-5'-exoribonuclease activity] GO:0000467 [exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0000738 [DNA catabolic process, exonucleolytic] GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0044822 [poly(A) RNA binding] GO:0046872 [metal ion binding] Show all	337 aa 37.2 kDa	No	0
ERI3-002 ENSP00000412291 ENST00000457571	F6UGJ8 [Direct mapping] ERI1 exoribonuclease 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000175 [3'-5'-exoribonuclease activity] GO:0000467 [exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0000738 [DNA catabolic process, exonucleolytic] GO:0003676 [nucleic acid binding] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	250 aa 27.4 kDa	No	0
ERI3-003 ENSP00000361333 ENST00000372259	O43414 [Direct mapping] ERI1 exoribonuclease 3 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000175 [3'-5'-exoribonuclease activity] GO:0000467 [exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0000738 [DNA catabolic process, exonucleolytic] GO:0003676 [nucleic acid binding] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0044822 [poly(A) RNA binding] GO:0046872 [metal ion binding] Show all	222 aa 25 kDa	No	0
ERI3-004 ENSP00000396764 ENST00000452396	F6QUN3 [Direct mapping] ERI1 exoribonuclease 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000175 [3'-5'-exoribonuclease activity] GO:0000467 [exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0000738 [DNA catabolic process, exonucleolytic] GO:0003676 [nucleic acid binding] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	176 aa 19.7 kDa	No	0
ERI3-006 ENSP00000390710 ENST00000456170	H0Y4B0 [Direct mapping] ERI1 exoribonuclease 3 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000175 [3'-5'-exoribonuclease activity] GO:0000467 [exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0000738 [DNA catabolic process, exonucleolytic] GO:0003676 [nucleic acid binding] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	204 aa 22.9 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.