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Cancer tissues were in general weakly stained or negative. Several cases of melanomas, ovarian and pancreatic cancers showed moderate cytoplasmic staining.
Melanomas showed moderate to strong cytoplasmic positivity while hepatocellular carcinomas, gliomas, breast, colorectal, lung and thyroid cancers showed weak to moderate staining. Remaining cancers were mainly negative.
GENE INFORMATION
Gene name
NENF (HGNC Symbol)
Synonyms
CIR2, SCIRP10, SPUF
Description
Neudesin neurotrophic factor (HGNC Symbol)
Entrez gene summary
This gene encodes a neurotrophic factor that may play a role in neuron differentiation and development. A pseudogene of this gene is found on chromosome 12. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2009]
