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A4GNT

GENERAL INFORMATION

Gene name

 A4GNT

Gene description

 Alpha-1,4-N-acetylglucosaminyltransferase

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (stomach)
GTEx:Group enriched (stomach, pancreas, kidney)
FANTOM5:Group enriched (gallbladder, pancreas)

Protein evidence

 Evidence at protein level

Protein expression

 Granular cytoplasmic expression in stomach.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Supported based on 1 antibody.
HPA008017
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (stomach)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (stomach, pancreas, kidney)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (gallbladder, pancreas)

GENE INFORMATION

Gene name

 A4GNT (HGNC Symbol)

Synonyms

 alpha4GnT

Description

 Alpha-1,4-N-acetylglucosaminyltransferase (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. [provided by RefSeq, Jul 2008]

Chromosome

 3

Cytoband

 q22.3

Chromosome location (bp)

 138123718 - 138132387

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000118017 (version 83.38)

Entrez gene

 51146

UniProt

 Q9UNA3 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9UNA3

Antibodypedia

 A4GNT antibodies

PROTEIN BROWSER
A4GNT-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
A4GNT-001
ENSP00000236709
ENST00000236709
Q9UNA3 [Direct mapping]
Alpha-1,4-N-acetylglucosaminyltransferase
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   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
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GO:0000139 [Golgi membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0006493 [protein O-linked glycosylation]
GO:0008375 [acetylglucosaminyltransferase activity]
GO:0009101 [glycoprotein biosynthetic process]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016266 [O-glycan processing]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0050680 [negative regulation of epithelial cell proliferation]
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 340 aa
39.5 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.