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APOA1

GENERAL INFORMATION

Gene name

 APOA1

Gene description

 Apolipoprotein A-I

Protein class

 Cancer-related genes
Candidate cardiovascular disease genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (liver, small intestine)
GTEx:Tissue enriched (liver)
FANTOM5:Group enriched (liver, small intestine)

Protein evidence

 Evidence at protein level

Protein expression

 Distinct plasma positivity in several tissues.

DATA RELIABILITY

Data reliability
description

 Secreted protein, tissue location of RNA and protein might differ and correlation is complex. Antibody staining in cells/structures not annotated, view images.

Reliability score

 Supported based on 2 antibodies.
HPA046715 , CAB016778
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Duodenum

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (liver, small intestine)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (liver)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (liver, small intestine)

GENE INFORMATION

Gene name

 APOA1

Synonyms

Description

 Apolipoprotein A-I (HGNC Symbol)

Entrez gene summary

 This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq, Jul 2008]

Chromosome

 11

Cytoband

 q23.3

Chromosome location (bp)

 116835751 - 116837950

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000118137 (version 83.38)

Entrez gene

 335

UniProt

 P02647 (UniProt - Evidence at protein level)

neXtProt

 NX_P02647

Antibodypedia

 APOA1 antibodies

PROTEIN BROWSER
APOA1-001
APOA1-002
APOA1-003
APOA1-004
APOA1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
APOA1-001
ENSP00000236850
ENST00000236850
P02647 [Direct mapping]
Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I
A0A024R3E3 [Target identity:100%; Query identity:100%]
Apolipoprotein A-I, isoform CRA_a
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001523 [retinoid metabolic process]
GO:0001540 [beta-amyloid binding]
GO:0001932 [regulation of protein phosphorylation]
GO:0001935 [endothelial cell proliferation]
GO:0002576 [platelet degranulation]
GO:0002740 [negative regulation of cytokine secretion involved in immune response]
GO:0005319 [lipid transporter activity]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005548 [phospholipid transporter activity]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005769 [early endosome]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006644 [phospholipid metabolic process]
GO:0006656 [phosphatidylcholine biosynthetic process]
GO:0006695 [cholesterol biosynthetic process]
GO:0006869 [lipid transport]
GO:0006898 [receptor-mediated endocytosis]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007229 [integrin-mediated signaling pathway]
GO:0007584 [response to nutrient]
GO:0007596 [blood coagulation]
GO:0007603 [phototransduction, visible light]
GO:0008035 [high-density lipoprotein particle binding]
GO:0008203 [cholesterol metabolic process]
GO:0008211 [glucocorticoid metabolic process]
GO:0008289 [lipid binding]
GO:0009986 [cell surface]
GO:0010804 [negative regulation of tumor necrosis factor-mediated signaling pathway]
GO:0010873 [positive regulation of cholesterol esterification]
GO:0010898 [positive regulation of triglyceride catabolic process]
GO:0010903 [negative regulation of very-low-density lipoprotein particle remodeling]
GO:0014012 [peripheral nervous system axon regeneration]
GO:0015485 [cholesterol binding]
GO:0015914 [phospholipid transport]
GO:0017127 [cholesterol transporter activity]
GO:0018158 [protein oxidation]
GO:0018206 [peptidyl-methionine modification]
GO:0019433 [triglyceride catabolic process]
GO:0019899 [enzyme binding]
GO:0019915 [lipid storage]
GO:0030139 [endocytic vesicle]
GO:0030168 [platelet activation]
GO:0030300 [regulation of intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0030325 [adrenal gland development]
GO:0031100 [organ regeneration]
GO:0031102 [neuron projection regeneration]
GO:0031210 [phosphatidylcholine binding]
GO:0031410 [cytoplasmic vesicle]
GO:0032489 [regulation of Cdc42 protein signal transduction]
GO:0033344 [cholesterol efflux]
GO:0033700 [phospholipid efflux]
GO:0034115 [negative regulation of heterotypic cell-cell adhesion]
GO:0034190 [apolipoprotein receptor binding]
GO:0034191 [apolipoprotein A-I receptor binding]
GO:0034361 [very-low-density lipoprotein particle]
GO:0034364 [high-density lipoprotein particle]
GO:0034365 [discoidal high-density lipoprotein particle]
GO:0034366 [spherical high-density lipoprotein particle]
GO:0034372 [very-low-density lipoprotein particle remodeling]
GO:0034375 [high-density lipoprotein particle remodeling]
GO:0034380 [high-density lipoprotein particle assembly]
GO:0034384 [high-density lipoprotein particle clearance]
GO:0034774 [secretory granule lumen]
GO:0035025 [positive regulation of Rho protein signal transduction]
GO:0042157 [lipoprotein metabolic process]
GO:0042158 [lipoprotein biosynthetic process]
GO:0042493 [response to drug]
GO:0042627 [chylomicron]
GO:0042632 [cholesterol homeostasis]
GO:0042802 [identical protein binding]
GO:0043534 [blood vessel endothelial cell migration]
GO:0043627 [response to estrogen]
GO:0043691 [reverse cholesterol transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0045499 [chemorepellent activity]
GO:0045723 [positive regulation of fatty acid biosynthetic process]
GO:0050713 [negative regulation of interleukin-1 beta secretion]
GO:0050728 [negative regulation of inflammatory response]
GO:0050821 [protein stabilization]
GO:0050919 [negative chemotaxis]
GO:0051006 [positive regulation of lipoprotein lipase activity]
GO:0051180 [vitamin transport]
GO:0051345 [positive regulation of hydrolase activity]
GO:0051346 [negative regulation of hydrolase activity]
GO:0051496 [positive regulation of stress fiber assembly]
GO:0055085 [transmembrane transport]
GO:0055091 [phospholipid homeostasis]
GO:0055102 [lipase inhibitor activity]
GO:0060192 [negative regulation of lipase activity]
GO:0060228 [phosphatidylcholine-sterol O-acyltransferase activator activity]
GO:0060354 [negative regulation of cell adhesion molecule production]
GO:0060761 [negative regulation of response to cytokine stimulus]
GO:0070062 [extracellular exosome]
GO:0070328 [triglyceride homeostasis]
GO:0070508 [cholesterol import]
GO:0070653 [high-density lipoprotein particle receptor binding]
GO:0071682 [endocytic vesicle lumen]
GO:0071813 [lipoprotein particle binding]
GO:0072562 [blood microparticle]
GO:1900026 [positive regulation of substrate adhesion-dependent cell spreading]
GO:1903561 [extracellular vesicle]
Show all
 267 aa
30.8 kDa 		Yes 0
APOA1-002
ENSP00000364469
ENST00000375320
P02647 [Direct mapping]
Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I
A0A024R3E3 [Target identity:100%; Query identity:100%]
Apolipoprotein A-I, isoform CRA_a
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001523 [retinoid metabolic process]
GO:0001540 [beta-amyloid binding]
GO:0002576 [platelet degranulation]
GO:0002740 [negative regulation of cytokine secretion involved in immune response]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005769 [early endosome]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006656 [phosphatidylcholine biosynthetic process]
GO:0006695 [cholesterol biosynthetic process]
GO:0006869 [lipid transport]
GO:0006898 [receptor-mediated endocytosis]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007229 [integrin-mediated signaling pathway]
GO:0007596 [blood coagulation]
GO:0007603 [phototransduction, visible light]
GO:0008203 [cholesterol metabolic process]
GO:0008289 [lipid binding]
GO:0010804 [negative regulation of tumor necrosis factor-mediated signaling pathway]
GO:0010873 [positive regulation of cholesterol esterification]
GO:0010898 [positive regulation of triglyceride catabolic process]
GO:0010903 [negative regulation of very-low-density lipoprotein particle remodeling]
GO:0015485 [cholesterol binding]
GO:0017127 [cholesterol transporter activity]
GO:0018158 [protein oxidation]
GO:0018206 [peptidyl-methionine modification]
GO:0019433 [triglyceride catabolic process]
GO:0019899 [enzyme binding]
GO:0030139 [endocytic vesicle]
GO:0030168 [platelet activation]
GO:0030300 [regulation of intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0031102 [neuron projection regeneration]
GO:0031210 [phosphatidylcholine binding]
GO:0031410 [cytoplasmic vesicle]
GO:0032489 [regulation of Cdc42 protein signal transduction]
GO:0033344 [cholesterol efflux]
GO:0033700 [phospholipid efflux]
GO:0034115 [negative regulation of heterotypic cell-cell adhesion]
GO:0034190 [apolipoprotein receptor binding]
GO:0034191 [apolipoprotein A-I receptor binding]
GO:0034361 [very-low-density lipoprotein particle]
GO:0034364 [high-density lipoprotein particle]
GO:0034366 [spherical high-density lipoprotein particle]
GO:0034372 [very-low-density lipoprotein particle remodeling]
GO:0034375 [high-density lipoprotein particle remodeling]
GO:0034380 [high-density lipoprotein particle assembly]
GO:0034384 [high-density lipoprotein particle clearance]
GO:0034774 [secretory granule lumen]
GO:0035025 [positive regulation of Rho protein signal transduction]
GO:0042157 [lipoprotein metabolic process]
GO:0042627 [chylomicron]
GO:0042632 [cholesterol homeostasis]
GO:0042802 [identical protein binding]
GO:0043691 [reverse cholesterol transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0045499 [chemorepellent activity]
GO:0045723 [positive regulation of fatty acid biosynthetic process]
GO:0050713 [negative regulation of interleukin-1 beta secretion]
GO:0050728 [negative regulation of inflammatory response]
GO:0050821 [protein stabilization]
GO:0050919 [negative chemotaxis]
GO:0051006 [positive regulation of lipoprotein lipase activity]
GO:0051180 [vitamin transport]
GO:0051345 [positive regulation of hydrolase activity]
GO:0051496 [positive regulation of stress fiber assembly]
GO:0055085 [transmembrane transport]
GO:0055091 [phospholipid homeostasis]
GO:0060228 [phosphatidylcholine-sterol O-acyltransferase activator activity]
GO:0060354 [negative regulation of cell adhesion molecule production]
GO:0060761 [negative regulation of response to cytokine stimulus]
GO:0070062 [extracellular exosome]
GO:0070328 [triglyceride homeostasis]
GO:0070508 [cholesterol import]
GO:0070653 [high-density lipoprotein particle receptor binding]
GO:0071682 [endocytic vesicle lumen]
GO:0072562 [blood microparticle]
GO:1900026 [positive regulation of substrate adhesion-dependent cell spreading]
GO:1903561 [extracellular vesicle]
Show all
 267 aa
30.8 kDa 		Yes 0
APOA1-003
ENSP00000364472
ENST00000375323
P02647 [Direct mapping]
Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I
A0A024R3E3 [Target identity:100%; Query identity:100%]
Apolipoprotein A-I, isoform CRA_a
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001523 [retinoid metabolic process]
GO:0001540 [beta-amyloid binding]
GO:0002576 [platelet degranulation]
GO:0002740 [negative regulation of cytokine secretion involved in immune response]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005769 [early endosome]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006656 [phosphatidylcholine biosynthetic process]
GO:0006695 [cholesterol biosynthetic process]
GO:0006869 [lipid transport]
GO:0006898 [receptor-mediated endocytosis]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007229 [integrin-mediated signaling pathway]
GO:0007596 [blood coagulation]
GO:0007603 [phototransduction, visible light]
GO:0008203 [cholesterol metabolic process]
GO:0008289 [lipid binding]
GO:0010804 [negative regulation of tumor necrosis factor-mediated signaling pathway]
GO:0010873 [positive regulation of cholesterol esterification]
GO:0010898 [positive regulation of triglyceride catabolic process]
GO:0010903 [negative regulation of very-low-density lipoprotein particle remodeling]
GO:0015485 [cholesterol binding]
GO:0017127 [cholesterol transporter activity]
GO:0018158 [protein oxidation]
GO:0018206 [peptidyl-methionine modification]
GO:0019433 [triglyceride catabolic process]
GO:0019899 [enzyme binding]
GO:0030139 [endocytic vesicle]
GO:0030168 [platelet activation]
GO:0030300 [regulation of intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0031102 [neuron projection regeneration]
GO:0031210 [phosphatidylcholine binding]
GO:0031410 [cytoplasmic vesicle]
GO:0032489 [regulation of Cdc42 protein signal transduction]
GO:0033344 [cholesterol efflux]
GO:0033700 [phospholipid efflux]
GO:0034115 [negative regulation of heterotypic cell-cell adhesion]
GO:0034190 [apolipoprotein receptor binding]
GO:0034191 [apolipoprotein A-I receptor binding]
GO:0034361 [very-low-density lipoprotein particle]
GO:0034364 [high-density lipoprotein particle]
GO:0034366 [spherical high-density lipoprotein particle]
GO:0034372 [very-low-density lipoprotein particle remodeling]
GO:0034375 [high-density lipoprotein particle remodeling]
GO:0034380 [high-density lipoprotein particle assembly]
GO:0034384 [high-density lipoprotein particle clearance]
GO:0034774 [secretory granule lumen]
GO:0035025 [positive regulation of Rho protein signal transduction]
GO:0042157 [lipoprotein metabolic process]
GO:0042627 [chylomicron]
GO:0042632 [cholesterol homeostasis]
GO:0042802 [identical protein binding]
GO:0043691 [reverse cholesterol transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0045499 [chemorepellent activity]
GO:0045723 [positive regulation of fatty acid biosynthetic process]
GO:0050713 [negative regulation of interleukin-1 beta secretion]
GO:0050728 [negative regulation of inflammatory response]
GO:0050821 [protein stabilization]
GO:0050919 [negative chemotaxis]
GO:0051006 [positive regulation of lipoprotein lipase activity]
GO:0051180 [vitamin transport]
GO:0051345 [positive regulation of hydrolase activity]
GO:0051496 [positive regulation of stress fiber assembly]
GO:0055085 [transmembrane transport]
GO:0055091 [phospholipid homeostasis]
GO:0060228 [phosphatidylcholine-sterol O-acyltransferase activator activity]
GO:0060354 [negative regulation of cell adhesion molecule production]
GO:0060761 [negative regulation of response to cytokine stimulus]
GO:0070062 [extracellular exosome]
GO:0070328 [triglyceride homeostasis]
GO:0070508 [cholesterol import]
GO:0070653 [high-density lipoprotein particle receptor binding]
GO:0071682 [endocytic vesicle lumen]
GO:0072562 [blood microparticle]
GO:1900026 [positive regulation of substrate adhesion-dependent cell spreading]
GO:1903561 [extracellular vesicle]
Show all
 267 aa
30.8 kDa 		Yes 0
APOA1-004
ENSP00000352471
ENST00000359492
P02647 [Direct mapping]
Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I
A0A024R3E3 [Target identity:100%; Query identity:100%]
Apolipoprotein A-I, isoform CRA_a
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Candidate cardiovascular disease genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001523 [retinoid metabolic process]
GO:0001540 [beta-amyloid binding]
GO:0002576 [platelet degranulation]
GO:0002740 [negative regulation of cytokine secretion involved in immune response]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005769 [early endosome]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006656 [phosphatidylcholine biosynthetic process]
GO:0006695 [cholesterol biosynthetic process]
GO:0006869 [lipid transport]
GO:0006898 [receptor-mediated endocytosis]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007229 [integrin-mediated signaling pathway]
GO:0007596 [blood coagulation]
GO:0007603 [phototransduction, visible light]
GO:0008203 [cholesterol metabolic process]
GO:0008289 [lipid binding]
GO:0010804 [negative regulation of tumor necrosis factor-mediated signaling pathway]
GO:0010873 [positive regulation of cholesterol esterification]
GO:0010898 [positive regulation of triglyceride catabolic process]
GO:0010903 [negative regulation of very-low-density lipoprotein particle remodeling]
GO:0015485 [cholesterol binding]
GO:0017127 [cholesterol transporter activity]
GO:0018158 [protein oxidation]
GO:0018206 [peptidyl-methionine modification]
GO:0019433 [triglyceride catabolic process]
GO:0019899 [enzyme binding]
GO:0030139 [endocytic vesicle]
GO:0030168 [platelet activation]
GO:0030300 [regulation of intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0031102 [neuron projection regeneration]
GO:0031210 [phosphatidylcholine binding]
GO:0031410 [cytoplasmic vesicle]
GO:0032489 [regulation of Cdc42 protein signal transduction]
GO:0033344 [cholesterol efflux]
GO:0033700 [phospholipid efflux]
GO:0034115 [negative regulation of heterotypic cell-cell adhesion]
GO:0034190 [apolipoprotein receptor binding]
GO:0034191 [apolipoprotein A-I receptor binding]
GO:0034361 [very-low-density lipoprotein particle]
GO:0034364 [high-density lipoprotein particle]
GO:0034366 [spherical high-density lipoprotein particle]
GO:0034372 [very-low-density lipoprotein particle remodeling]
GO:0034375 [high-density lipoprotein particle remodeling]
GO:0034380 [high-density lipoprotein particle assembly]
GO:0034384 [high-density lipoprotein particle clearance]
GO:0034774 [secretory granule lumen]
GO:0035025 [positive regulation of Rho protein signal transduction]
GO:0042157 [lipoprotein metabolic process]
GO:0042627 [chylomicron]
GO:0042632 [cholesterol homeostasis]
GO:0042802 [identical protein binding]
GO:0043691 [reverse cholesterol transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0045499 [chemorepellent activity]
GO:0045723 [positive regulation of fatty acid biosynthetic process]
GO:0050713 [negative regulation of interleukin-1 beta secretion]
GO:0050728 [negative regulation of inflammatory response]
GO:0050821 [protein stabilization]
GO:0050919 [negative chemotaxis]
GO:0051006 [positive regulation of lipoprotein lipase activity]
GO:0051180 [vitamin transport]
GO:0051345 [positive regulation of hydrolase activity]
GO:0051496 [positive regulation of stress fiber assembly]
GO:0055085 [transmembrane transport]
GO:0055091 [phospholipid homeostasis]
GO:0060228 [phosphatidylcholine-sterol O-acyltransferase activator activity]
GO:0060354 [negative regulation of cell adhesion molecule production]
GO:0060761 [negative regulation of response to cytokine stimulus]
GO:0070062 [extracellular exosome]
GO:0070328 [triglyceride homeostasis]
GO:0070508 [cholesterol import]
GO:0070653 [high-density lipoprotein particle receptor binding]
GO:0071682 [endocytic vesicle lumen]
GO:0072562 [blood microparticle]
GO:1900026 [positive regulation of substrate adhesion-dependent cell spreading]
GO:1903561 [extracellular vesicle]
Show all
 267 aa
30.8 kDa 		Yes 0
APOA1-005
ENSP00000364478
ENST00000375329
F8W696 [Direct mapping]
Apolipoprotein A-I
Show all
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005576 [extracellular region]
GO:0006695 [cholesterol biosynthetic process]
GO:0006869 [lipid transport]
GO:0008289 [lipid binding]
GO:0010898 [positive regulation of triglyceride catabolic process]
GO:0019433 [triglyceride catabolic process]
GO:0030300 [regulation of intestinal cholesterol absorption]
GO:0031102 [neuron projection regeneration]
GO:0031210 [phosphatidylcholine binding]
GO:0034372 [very-low-density lipoprotein particle remodeling]
GO:0042157 [lipoprotein metabolic process]
GO:0042627 [chylomicron]
GO:0045723 [positive regulation of fatty acid biosynthetic process]
GO:0051006 [positive regulation of lipoprotein lipase activity]
Show all
 245 aa
27.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.