We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
High mobility group nucleosomal binding domain 3 (HGNC Symbol)
Entrez gene summary
Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
A0A087WZE9 [Direct mapping] High mobility group nucleosome-binding domain-containing protein 3
Show all
Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000785 [chromatin] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0031492 [nucleosomal DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity] GO:0061178 [regulation of insulin secretion involved in cellular response to glucose stimulus]