Cell atlas - DNAH7 - The Human Protein Atlas

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DNAH7

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	DNAH7
Gene description	Dynein, axonemal, heavy chain 7
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Cell line enhanced (PC-3)
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA044070
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (PC-3) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA044070	PC-3	Cytosol
	HPA044070	SH-SY5Y	Cytosol
	HPA044070	U-2 OS	Cytosol

GENE INFORMATION
Gene name	DNAH7 (HGNC Symbol)
Synonyms	KIAA0944
Description	Dynein, axonemal, heavy chain 7 (HGNC Symbol)
Entrez gene summary	DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	q32.3
Chromosome location (bp)	195737703 - 196068812
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000118997 (version 83.38)
Entrez gene	56171
UniProt	Q8WXX0 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WXX0
Antibodypedia	DNAH7 antibodies

PROTEIN BROWSER

DNAH7-001	DNAH7-002	DNAH7-003	DNAH7-006	DNAH7-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DNAH7-001 ENSP00000311273 ENST00000312428	Q8WXX0 [Direct mapping] Dynein heavy chain 7, axonemal Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001539 [cilium or flagellum-dependent cell motility] GO:0003341 [cilium movement] GO:0003777 [microtubule motor activity] GO:0005509 [calcium ion binding] GO:0005524 [ATP binding] GO:0005858 [axonemal dynein complex] GO:0005874 [microtubule] GO:0005929 [cilium] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] GO:0030286 [dynein complex] GO:0036156 [inner dynein arm] GO:0036159 [inner dynein arm assembly] Show all	4024 aa 461.2 kDa	No	0
DNAH7-002 ENSP00000386260 ENST00000410072	Q8WXX0 [Direct mapping] Dynein heavy chain 7, axonemal Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001539 [cilium or flagellum-dependent cell motility] GO:0003341 [cilium movement] GO:0003777 [microtubule motor activity] GO:0005509 [calcium ion binding] GO:0005524 [ATP binding] GO:0005858 [axonemal dynein complex] GO:0005874 [microtubule] GO:0005929 [cilium] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] GO:0036156 [inner dynein arm] GO:0036159 [inner dynein arm assembly] Show all	501 aa 57.7 kDa	No	0
DNAH7-003 ENSP00000407444 ENST00000427816	C9JUY3 [Direct mapping] Dynein heavy chain 7, axonemal Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		121 aa 13.6 kDa	No	0
DNAH7-006 ENSP00000409732 ENST00000438565	H7C362 [Direct mapping] Dynein heavy chain 7, axonemal Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		56 aa 6.8 kDa	No	0
DNAH7-008 ENSP00000386912 ENST00000409063	Q8WXX0 [Direct mapping] Dynein heavy chain 7, axonemal Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001539 [cilium or flagellum-dependent cell motility] GO:0003341 [cilium movement] GO:0003777 [microtubule motor activity] GO:0005509 [calcium ion binding] GO:0005524 [ATP binding] GO:0005858 [axonemal dynein complex] GO:0005874 [microtubule] GO:0005929 [cilium] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] GO:0030286 [dynein complex] GO:0036156 [inner dynein arm] GO:0036159 [inner dynein arm assembly] Show all	507 aa 58 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.