Tissue expression of PTBP3 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PTBP3
Gene description	Polypyrimidine tract binding protein 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	PTBP3 (HGNC Symbol)
Synonyms	DKFZp781I1117, ROD1
Description	Polypyrimidine tract binding protein 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Chromosome	9
Cytoband	q32
Chromosome location (bp)	112217716 - 112333667
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000119314 (version 83.38)
Entrez gene	9991
UniProt	O95758 (UniProt - Evidence at protein level)
neXtProt	NX_O95758
Antibodypedia	PTBP3 antibodies

PROTEIN BROWSER

PTBP3-001	PTBP3-003	PTBP3-004	PTBP3-005	PTBP3-006	PTBP3-201	PTBP3-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PTBP3-001 ENSP00000210227 ENST00000210227	X6R242 [Direct mapping] Polypyrimidine tract-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	183 aa 19.6 kDa	No	0
PTBP3-003 ENSP00000388024 ENST00000450374	B1ALY4 [Direct mapping] Polypyrimidine tract-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		77 aa 8.3 kDa	No	0
PTBP3-004 ENSP00000363375 ENST00000374257	O95758 [Direct mapping] Polypyrimidine tract-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0009653 [anatomical structure morphogenesis] GO:0033119 [negative regulation of RNA splicing] GO:0043249 [erythrocyte maturation] GO:0044822 [poly(A) RNA binding] Show all	524 aa 56.8 kDa	No	0
PTBP3-005 ENSP00000340705 ENST00000343327	O95758 [Direct mapping] Polypyrimidine tract-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0009653 [anatomical structure morphogenesis] GO:0033119 [negative regulation of RNA splicing] GO:0043249 [erythrocyte maturation] GO:0044822 [poly(A) RNA binding] Show all	457 aa 49.5 kDa	No	0
PTBP3-006 ENSP00000363373 ENST00000374255	O95758 [Direct mapping] Polypyrimidine tract-binding protein 3 A0A024R163 [Target identity:100%; Query identity:100%] ROD1 regulator of differentiation 1 (S. pombe), isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0009653 [anatomical structure morphogenesis] GO:0033119 [negative regulation of RNA splicing] GO:0043249 [erythrocyte maturation] GO:0044822 [poly(A) RNA binding] Show all	552 aa 59.7 kDa	No	0
PTBP3-201 ENSP00000334499 ENST00000334318	O95758 [Direct mapping] Polypyrimidine tract-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0009653 [anatomical structure morphogenesis] GO:0033119 [negative regulation of RNA splicing] GO:0043249 [erythrocyte maturation] GO:0044822 [poly(A) RNA binding] Show all	555 aa 60 kDa	No	0
PTBP3-202 ENSP00000414921 ENST00000458258	O95758 [Direct mapping] Polypyrimidine tract-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0009653 [anatomical structure morphogenesis] GO:0033119 [negative regulation of RNA splicing] GO:0043249 [erythrocyte maturation] GO:0044822 [poly(A) RNA binding] GO:0045595 [regulation of cell differentiation] GO:0048025 [negative regulation of mRNA splicing, via spliceosome] Show all	558 aa 60.4 kDa	No	0