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NEK9

GENERAL INFORMATION

Gene name

 NEK9

Gene description

 NIMA-related kinase 9

Protein class

 Enzymes
Plasma proteins
Predicted intracellular proteins
Transporters

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in a few tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA001405
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Rectum

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 NEK9 (HGNC Symbol)

Synonyms

 DKFZp434D0935, MGC16714, Nek8, NERCC

Description

 NIMA-related kinase 9 (HGNC Symbol)

Entrez gene summary

Chromosome

 14

Cytoband

 q24.3

Chromosome location (bp)

 75079353 - 75127344

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000119638 (version 83.38)

Entrez gene

 91754

UniProt

 Q8TD19 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TD19

Antibodypedia

 NEK9 antibodies

PROTEIN BROWSER
NEK9-001
NEK9-005
NEK9-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NEK9-001
ENSP00000238616
ENST00000238616
Q8TD19 [Direct mapping]
Serine/threonine-protein kinase Nek9
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   NEK Ser/Thr protein kinases
Transporters
   Transporter channels and pores
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000278 [mitotic cell cycle]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0006468 [protein phosphorylation]
GO:0007067 [mitotic nuclear division]
GO:0007077 [mitotic nuclear envelope disassembly]
GO:0019901 [protein kinase binding]
GO:0046872 [metal ion binding]
GO:0051301 [cell division]
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 979 aa
107.2 kDa 		No 0
NEK9-005
ENSP00000452537
ENST00000553823
G3V5V0 [Direct mapping]
Serine/threonine-protein kinase Nek9
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   Phobius predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
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 73 aa
8.5 kDa 		No 0
NEK9-006
ENSP00000450943
ENST00000557673
G3V2Z5 [Direct mapping]
Serine/threonine-protein kinase Nek9
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   Phobius predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 128 aa
14.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.